Evidence map›Paper›PMID 34349174›Full record

ArticleScientific reports2021

Postsystolic thickening is a potential new clinical sign of injured myocardium in marfan syndrome.

Aleksandra Mas-Stachurska, Gustavo Egea, Rianne de Bruin-Bon, Paula Rudenick, Laura Sanchis, Berto J Bouma, Barbara J Mulder, Bart Bijnens, Marta Sitges

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Aleksandra Mas-StachurskaCardiovascular Institute, Hospital Clinic, University of Barcelona and Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS); CERCA Programme/Generalitat de Catalunya, Barcelona, Spain. astachur@gmail.com.
Gustavo EgeaDepartment of Biomedical Sciences, University of Barcelona School of Medicine and Health Sciences and Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.
Rianne de Bruin-BonCardiology Department, Amsterdam University Medical Centers, Location Academic Medic Centrum, Amsterdam, The Netherlands.
Paula RudenickICREA, Barcelona, Spain.
Laura SanchisCardiovascular Institute, Hospital Clinic, University of Barcelona and Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS); CERCA Programme/Generalitat de Catalunya, Barcelona, Spain.
Berto J BoumaCardiology Department, Amsterdam University Medical Centers, Location Academic Medic Centrum, Amsterdam, The Netherlands.
Barbara J MulderCardiology Department, Amsterdam University Medical Centers, Location Academic Medic Centrum, Amsterdam, The Netherlands.
Bart Bijnens *Cardiovascular Institute, Hospital Clinic, University of Barcelona and Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS); CERCA Programme/Generalitat de Catalunya, Barcelona, Spain.
Marta Sitges *Cardiovascular Institute, Hospital Clinic, University of Barcelona School of Medicine and Health Sciences and Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), CIBERCV, Instituto de Salud Carlos III (CB16/11/00354); CERCA Programme/Generalitat de Catalunya, Barcelona, Spain.
Amsterdam University Medical Centers · NLCardiovascular Institute Hospital · JPConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESInstitució Catalana de Recerca i Estudis Avançats · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms leading to cardiac remodeling in Marfan syndrome (MFS) are a matter of debate since it could be either due to structural dysfunction of the myocardial extracellular matrix or to increased afterload caused by the dilated aorta. We aim to characterize the presence of abnormal myocardial function in MFS and to investigate its potential association with increased afterload. Aorta, left ventricle (LV) and the postsystolic thickening (PST) were analyzed in echocardiography in Fbn1

Indexed as

AnimalsAortaDisease Models, AnimalHeart VentriclesHumansMarfan SyndromeMiceMice, Inbred C57BLMyocardiumVentricular Function, Left

Identifiers

PMID34349174
PMCPMC8338999
OpenAlexW3191787067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.