Evidence map›Paper›PMID 34349169›Full record

ArticleScientific reports2021

Deciphering the biology of KIR2DL3

Gaëlle David, Catherine Willem, Nolwenn Legrand, Zakia Djaoud, Pierre Mérieau, Alexandre Walencik, Thierry Guillaume, Katia Gagne, Patrice Chevallier, Christelle Retière

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Virtual Memory CD8Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Gaëlle DavidEtablissement Français du Sang-Pays de la Loire, Blood Bank, 34 boulevard Jean Monnet, 44011, Nantes Cedex 01, France.
Catherine WillemEtablissement Français du Sang-Pays de la Loire, Blood Bank, 34 boulevard Jean Monnet, 44011, Nantes Cedex 01, France.
Nolwenn LegrandEtablissement Français du Sang-Pays de la Loire, Blood Bank, 34 boulevard Jean Monnet, 44011, Nantes Cedex 01, France.
Zakia DjaoudEtablissement Français du Sang-Pays de la Loire, Blood Bank, 34 boulevard Jean Monnet, 44011, Nantes Cedex 01, France.
Pierre MérieauEtablissement Français du Sang-Pays de la Loire, Blood Bank, 34 boulevard Jean Monnet, 44011, Nantes Cedex 01, France.
Alexandre WalencikEtablissement Français du Sang-Pays de la Loire, Blood Bank, 34 boulevard Jean Monnet, 44011, Nantes Cedex 01, France.
Thierry GuillaumeCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, 44000, Nantes, France.
Katia GagneEtablissement Français du Sang-Pays de la Loire, Blood Bank, 34 boulevard Jean Monnet, 44011, Nantes Cedex 01, France.
Patrice ChevallierCRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, 44000, Nantes, France.
Christelle RetièreEtablissement Français du Sang-Pays de la Loire, Blood Bank, 34 boulevard Jean Monnet, 44011, Nantes Cedex 01, France. christelle.retiere@efs.sante.fr.
Établissement Français du Sang · FRCentre Hospitalier Universitaire de Nantes · FRInserm · FRNantes Université · FRUniversité d'Angers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

KIR are mainly expressed on NK cells and to a lesser extent on T lymphocytes. Although the KIR NK cell repertoire was well explored in haploidentical Hematopoietic Stem Cell Transplantation (HSCT), KIR T cell compartment remains to be investigated in this context. In this study, the investigation of NK receptors on T lymphocytes during immune reconstitution after T-cell-replete haploidentical HSCT with Post-Transplant Cyclophosphamide (PTCy) has shown a significant increase of KIR2DL2/3

Indexed as

Hematopoietic Stem Cell TransplantationImmune ReconstitutionReceptors, KIRReceptors, KIR2DL3Transplantation, HaploidenticalCyclophosphamideHumansInterleukin-15Killer Cells, NaturalRecurrenceT-LymphocytesCyclophosphamideInterleukin-15KIR2DL3 protein, humanReceptors, KIRReceptors, KIR2DL3

Identifiers

PMID34349169
PMCPMC8338934
OpenAlexW3187797320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.