Evidence map›Paper›PMID 34349114›Full record

ArticleNature communications2021

Porous functionalized polymers enable generating and transporting hyperpolarized mixtures of metabolites.

Théo El Daraï, Samuel F Cousin, Quentin Stern, Morgan Ceillier, James Kempf, Dmitry Eshchenko, Roberto Melzi, Marc Schnell, Laurent Gremillard, Aurélien Bornet and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 56 citations in OpenAlex.

  1. AutomatedAnalytical chemistry · 2026
    Article
  2. Across-cities transportableNature communications · 2026
    Article
  3. Review
  4. Article
  5. BoostingScience advances · 2024
    Article
  6. Article
  7. The journal of physical chemistry letters · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Signal enhancement of hyperpolarizedNMR in biomedicine · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Théo El DaraïUniversité de Lyon, Centre de RMN à Très Hauts Champs de Lyon, UMR5082 - CNRS/UCBL/ENS de Lyon, Villeurbanne, France.
Samuel F CousinUniversité de Lyon, Centre de RMN à Très Hauts Champs de Lyon, UMR5082 - CNRS/UCBL/ENS de Lyon, Villeurbanne, France. samuel.cousin@univ-amu.fr.
Quentin SternUniversité de Lyon, Centre de RMN à Très Hauts Champs de Lyon, UMR5082 - CNRS/UCBL/ENS de Lyon, Villeurbanne, France.
Morgan CeillierUniversité de Lyon, Centre de RMN à Très Hauts Champs de Lyon, UMR5082 - CNRS/UCBL/ENS de Lyon, Villeurbanne, France.
James KempfBruker Biospin, Billerica, MA, USA.
Dmitry EshchenkoBruker Biospin, Fallanden, Switzerland.
Roberto MelziBruker Italia Srl, Milano, Italy.
Marc SchnellBruker Biospin, Fallanden, Switzerland.
Laurent GremillardUniversité de Lyon, INSA Lyon, MATEIS UMR CNRS 5510, Bât. Blaise Pascal, Villeurbanne, France.ORCID http://orcid.org/0000-0001-7258-6483
Aurélien BornetUniversité de Lyon, Centre de RMN à Très Hauts Champs de Lyon, UMR5082 - CNRS/UCBL/ENS de Lyon, Villeurbanne, France.
Jonas MilaniUniversité de Lyon, Centre de RMN à Très Hauts Champs de Lyon, UMR5082 - CNRS/UCBL/ENS de Lyon, Villeurbanne, France.
Basile VuichoudUniversité de Lyon, Centre de RMN à Très Hauts Champs de Lyon, UMR5082 - CNRS/UCBL/ENS de Lyon, Villeurbanne, France.
Olivier CalaUniversité de Lyon, Centre de RMN à Très Hauts Champs de Lyon, UMR5082 - CNRS/UCBL/ENS de Lyon, Villeurbanne, France.
Damien MontarnalUniversité de Lyon, CPE Lyon, CNRS, Catalyse, Chimie, Polymères et Procédés, UMR 5265, Lyon, France. damien.montarnal@univ-lyon1.fr.ORCID http://orcid.org/0000-0003-3246-3467
Sami JanninUniversité de Lyon, Centre de RMN à Très Hauts Champs de Lyon, UMR5082 - CNRS/UCBL/ENS de Lyon, Villeurbanne, France.ORCID http://orcid.org/0000-0002-8877-4929
Université Claude Bernard Lyon 1 · FRBruker (France) · FRBruker (Switzerland) · CHBruker (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperpolarization by dissolution dynamic nuclear polarization (dDNP) has enabled promising applications in spectroscopy and imaging, but remains poorly widespread due to experimental complexity. Broad democratization of dDNP could be realized by remote preparation and distribution of hyperpolarized samples from dedicated facilities. Here we show the synthesis of hyperpolarizing polymers (HYPOPs) that can generate radical- and contaminant-free hyperpolarized samples within minutes with lifetimes exceeding hours in the solid state. HYPOPs feature tunable macroporous porosity, with porous volumes up to 80% and concentration of nitroxide radicals grafted in the bulk matrix up to 285 μmol g

Identifiers

PMID34349114
PMCPMC8338986
OpenAlexW3190692259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.