Evidence map›Paper›PMID 34349101›Full record

ArticleSpinal cord series and cases2021

Evaluation of safety and performance of the self balancing walking system Atalante in patients with complete motor spinal cord injury.

Jacques Kerdraon, Jean Gabriel Previnaire, Maegan Tucker, Pauline Coignard, Willy Allegre, Emmanuel Knappen, Aaron Ames

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Spinal cord series and cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07767955 (Healthcare Professionals' Satisfaction With Various Exoskeleton Models), which is not on this map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07767955 completednot on this mapstarted 2024, after this paper: background citation

Healthcare Professionals' Satisfaction With Various Exoskeleton Models

TypeobservationalSponsorUniversity of Sao Paulo General HospitalRan2024 to 2025Enrolled14ConditionsParaplegia and TetraplegiaArmsExoskeleton
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jacques KerdraonCentre Mutualiste de Kerpape, Ploemeur Cedex, France. jkerdraon@kerpape.mutualite56.fr.
Jean Gabriel PrevinaireCentre Jacques Calvé - Fondation Hopale, Berck-sur-Mer Cedex, France.
Maegan TuckerCalifornia Institute of Technology, Pasadena, CA, USA.
Pauline CoignardCentre Mutualiste de Kerpape, Ploemeur Cedex, France.
Willy AllegreCentre Mutualiste de Kerpape, Ploemeur Cedex, France.
Emmanuel KnappenCentre Jacques Calvé - Fondation Hopale, Berck-sur-Mer Cedex, France.
Aaron AmesCalifornia Institute of Technology, Pasadena, CA, USA.
Clinique Mutualiste de l'Estuaire · FRCalifornia Institute of Technology · USFondation Hopale · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designProspective, open label, observational.

objectivesTo present results of the first clinical study on a newly developed robotic exoskeleton (Atalante®, Wandercraft, Paris, France) that enables individuals with spinal cord injury (SCI) to perform ambulatory functions without technical aids.

settingTwo sites specialized in SCI rehabilitation, France.

methodsInclusion criteria were presence of chronic complete SCI (AIS A) ranging from T5 to T12. The study protocol included 12 one-hour training sessions during 3 weeks. Patients walked on floor with robotic assistance and wore a harness connected to a mobile suspension system (without weight-bearing) to prevent from falling. Main outcome was the ability to walk 10 meters unassisted, secondary outcomes were assessment of other ambulatory functions, bladder and bowel functions, pain and spasticity.

resultsTwelve patients were enrolled, and 11 completed the protocol, mean age 33,9 years. Six patients had T6 levels of lesion or above. Seven patients passed the 10mWT at the 12th session unassisted (mean walking speed 0.13 m/s) while four required some human help. All patients succeeded at the other ambulatory tests (stand-up, sit-down, balance, turn). There were no significant change for bladder (Qualiveen) or bowel (NBD) functions, neuropathic pain (NPSI, NPRS), yet five patients reported a subjective improvement of their bowel function. Impact on spasticity was variable depending on the muscle examined (Ashworth). Ischial skin erosion was seen in one patient that needed local dressing.

conclusionThe Atalante system is safe and enables to perform ambulatory functions in patients with complete SCI.

Indexed as

Exoskeleton DeviceRoboticsSpinal Cord InjuriesHumansProspective StudiesWalking

Identifiers

PMID34349101
PMCPMC8338982
OpenAlexW3188630041

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.