Evidence map›Paper›PMID 34349002›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Cortical Visual Mapping following Ocular Gene Augmentation Therapy for Achromatopsia.

Ayelet McKyton, Edward Averbukh, Devora Marks Ohana, Netta Levin, Eyal Banin

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Clinical and genetic features ofFrontiers in medicine · 2025
    Article
  6. Recombinant adeno-associated virus as a delivery platform for ocular gene therapy: A comprehensive review.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Phenotype and genotype of 15 Saudi patients with achromatopsia: A case series.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ayelet McKytonfMRI Unit, Department of Neurology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Edward AverbukhCenter for Retinal and Macular Degenerations (CRMD), Department of Ophthalmology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Devora Marks OhanaCenter for Retinal and Macular Degenerations (CRMD), Department of Ophthalmology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Netta LevinfMRI Unit, Department of Neurology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel netta@hadassah.org.il.
Eyal BaninCenter for Retinal and Macular Degenerations (CRMD), Department of Ophthalmology, Hadassah Medical Organization and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Hebrew University of Jerusalem · ILHadassah Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of the adult human brain to develop function following correction of congenital deafferentation is controversial. Specifically, cases of recovery from congenital visual deficits are rare.

Indexed as

Magnetic Resonance ImagingAdultBrain MappingColor PerceptionColor Vision DefectsCyclic Nucleotide-Gated Cation ChannelsElectroretinographyFemaleFixation, OcularGene DuplicationGenetic TherapyGenetic VectorsHumansInjections, IntraocularMaleMutation, MissenseCNGA3 protein, humanCyclic Nucleotide-Gated Cation Channelsachromatopsiacolorplasticitypopulation-receptive fieldvisionvisual cortex

Identifiers

PMID34349002
PMCPMC8412991
OpenAlexW3190165961

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.