Evidence map›Paper›PMID 34348856›Full record

ArticleBrazilian journal of otorhinolaryngology

Olfactory neuroepithelium in the middle turbinate: is there any impact on olfaction function after lateral marsupialization for concha bullosa surgery?

Onur İsmi, Feyzi Meşe, Harun Gür, İclal Gürses, Yusuf Vayısoğlu, Kemal Görür, Cengiz Özcan

Abstract read
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Prevalence and Associated Factors of Olfactory and Gustatory Loss in Patients With Nasal Septal Deviation.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Onur İsmiUniversity of Mersin, Faculty of Medicine, Department of Otorhinolaryngology, Mersin, Turkey. Electronic address: dronurismi@gmail.com.
Feyzi MeşeSpecial Batman Dünya Hospital, Otorhinolaryngology specialist, Batman, Turkey.
Harun GürUniversity of Mersin, Faculty of Medicine, Department of Otorhinolaryngology, Mersin, Turkey.
İclal GürsesUniversity of İstanbul, Cerrahpaşa Faculty of Medicine, Department of Pathology, İstanbul, Turkey.
Yusuf VayısoğluUniversity of Mersin, Faculty of Medicine, Department of Otorhinolaryngology, Mersin, Turkey.
Kemal GörürUniversity of Mersin, Faculty of Medicine, Department of Otorhinolaryngology, Mersin, Turkey.
Cengiz ÖzcanUniversity of Mersin, Faculty of Medicine, Department of Otorhinolaryngology, Mersin, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe effect of the quantity of olfactory neuroepithelium in the middle turbinate on the postoperative olfactory function for middle turbinate concha bullosa patients has not yet been evaluated.

objectiveThe primary aim of this study was to investigate the olfactory structures in the middle turbinate by immunohistochemical analysis of the olfactory marker protein and to correlate the immunostaining results with the olfaction test results for patients with middle turbinate concha bullosa.

methodsSurgical materials of 18 middle turbinate concha bullosa patients who had undergone lateral marsupialization surgery were immunostained with olfactory marker protein antibodies. Smell diskettes olfaction test was applied to all of the study group patients both preoperatively and three months postoperatively. A visual analog scale was used to quantify the sense of nasal obstruction.

resultsIt was observed that the postoperative smell scores and the nasal obstruction visual analog scale values were significantly improved as compared to the preoperative values (p < 0.05). In addition, there was a significant correlation between the smell score gain and the visual analog scale gain values (r = 0.682). Results also indicated no significant correlation between the olfactory marker protein staining scores and the smell scores (p > 0.05).

conclusionThis first paper demonstrated that the quantity of the olfactory mucosa in the middle turbinate was not a determining factor for the postoperative smell function degree for middle turbinate concha bullosa patients. The underlying cause of the olfactory deficit for middle turbinate concha bullosa patients seems to be obstruction related rather than the middle turbinate's olfactory mucosa containing status.

Indexed as

Nasal ObstructionNose DiseasesHumansOlfactory Marker ProteinSmellTurbinatesOlfactory Marker ProteinConcha bullosaLateral marsupializationMiddle turbinate concha bullosaOlfactionOlfactory membrane protein

Identifiers

PMID34348856
PMCPMC9800953

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.