Evidence map›Paper›PMID 34348313›Full record

ArticleMedical principles and practice : international journal of the Kuwait University, Health Science Centre

Oral Health Status and Nutritional Habits as Predictors for Developing Alzheimer's Disease.

Aleksandra Popovac, Asja Čelebić, Sanja Peršić, Elka Stefanova, Aleksandra Milić Lemić, Ivica Stančić

Open access · diamondAbstract read
In one paragraph

Article in Medical principles and practice : international journal of the Kuwait University, Health Science Centre. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  13. Subjective and Objective Assessment of Chewing Performance in Older Adults with Different Dental Occlusion.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Aleksandra PopovacClinic for Prosthodontics, School of Dental Medicine, University of Belgrade, Belgrade, Serbia.
Asja ČelebićDepartment of Removable Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Sanja PeršićDepartment of Removable Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Elka StefanovaClinic for Neurology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Aleksandra Milić LemićClinic for Prosthodontics, School of Dental Medicine, University of Belgrade, Belgrade, Serbia.
Ivica StančićClinic for Prosthodontics, School of Dental Medicine, University of Belgrade, Belgrade, Serbia.
University of Belgrade · RSUniversity of Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePoor oral health, mainly tooth loss, has been suggested to pose a risk factor for Alzheimer's disease (AD). The nature of this relationship can be explained by mastication deficit and nutritional status. Also, the influence of nutritional parameters on cognitive impairment has been documented. The aim of this study was to investigate whether poor dental status and nutrition habits can be potential separate or associated risk factors for development of the AD.

methodsThe study sample included 116 patients with AD and 63 controls. Sociodemographic variables were investigated as factors potentially associated with AD. Dental examination included recording the number of natural teeth, presence of fixed or removable dentures, and the number of functional tooth units (FTUs). Nutritional status analysis included qualitative nutrition information, body mass index, serum albumin level, food consistency, and need for assistance in feeding. Regression analysis was used to investigate the predictors for development of AD.

resultsVariables with significant differences between groups, which were analyzed by using the binary regression analysis, were marital status, residence, number of total FTUs (no matter whether the contacts were between natural teeth or dentures), eating meat/fish and fruits/vegetables, food consistency, and serum albumin level. Logistic regression analysis showed that being single/widowed/divorced, eating more meat/fish or fruit/vegetable, eating blended/mashed/liquid food, having low levels of serum albumin, and having less FTUs were significant predictors for developing dementia.

conclusionHaving fewer occlusal contacts, consumption of soft food, and lower serum albumin levels can be considered as associated risk factors for AD.

Indexed as

Alzheimer DiseaseDietNutritional StatusOral HealthAgedCase-Control StudiesFeeding BehaviorFemaleHabitsHumansMaleSerum AlbuminSocioeconomic FactorsSerum AlbuminAlzheimer’s diseaseFood consistencyOral healthSerum albumin

Identifiers

PMID34348313
PMCPMC8562035
OpenAlexW3181560506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.