Evidence map›Paper›PMID 34348178›Full record

ArticleJournal of pain and symptom management2022

Characteristics of Cancer-Related Fatigue and Concomitant Sleep Disturbance in Cancer Patients.

Ivan H C Wu, Diwakar D Balachandran, Saadia A Faiz, Lara Bashoura, Carmen P Escalante, Ellen F Manzullo

Abstract read
In one paragraph

Article in Journal of pain and symptom management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Mechanisms of simplified sitting Badunjin effects on symptom burden: a network-based cross-lagged analysis in advanced cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  7. Trial
  8. Cancer-related cognitive impairment in adult cancer survivors: a clinical practice review for healthcare providers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  9. Symptom burden in cancer survivorship: insights from a survivorship program's patient-reported outcomes database.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  10. Clinical insights into the management of sleep disturbances within cancer care: a qualitative analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  11. Cancer-related fatigue in cancer survivors: an updated clinical practice review for healthcare providers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Relationship between fatigue and self-compassion and associated factors in patients with hematological cancer: A cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ivan H C WuDepartments of Health Disparities Research, University of Texas MD Anderson Cancer Center (I.H.C.W.), Houston, TX, USA. Electronic address: ihwu@mdanderson.org.
Diwakar D BalachandranDepartments of Pulmonary Medicine, University of Texas MD Anderson Cancer Center (D.D.B., S.A.F., L.B.), Houston, TX, USA.
Saadia A FaizDepartments of Pulmonary Medicine, University of Texas MD Anderson Cancer Center (D.D.B., S.A.F., L.B.), Houston, TX, USA.
Lara BashouraDepartments of Pulmonary Medicine, University of Texas MD Anderson Cancer Center (D.D.B., S.A.F., L.B.), Houston, TX, USA.
Carmen P EscalanteDepartments of General Internal Medicine, University of Texas MD Anderson Cancer Center (C.P.E., E.F.M.), Houston, TX, USA.
Ellen F ManzulloDepartments of General Internal Medicine, University of Texas MD Anderson Cancer Center (C.P.E., E.F.M.), Houston, TX, USA.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Social determinants of sleep and obesity: Disparities in African AmericansK99MD015296 · NIMHD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WU, IVAN H · 2021 to 2022
$194k
NCI NIH HHS P30 CA016672NIMHD NIH HHS K99 MD015296
6 · The paper itself

Abstract

contextCancer patients often experience cancer-related fatigue (CRF) and sleep disturbances due to cancer and cancer treatment, and symptoms can persist long after treatment. Despite these common occurrences, few studies simultaneously characterize CRF and sleep architecture among cancer patients.

objectivesThe objective was to characterize CRF and the sleep architecture of patients seen in a CRF clinic and sleep clinic at the University of Texas MD Anderson Cancer Center.

methodsCRF Clinic medical records were retrospectively reviewed from September 1, 2006, to September 30, 2010, for self-reported performance status, fatigue, pain, sleep disturbance, depression, anxiety, and sleepiness (n = 219). Polysomnography results were recorded for those referred for additional sleep consultation (n = 39).

resultsNotably, patients often reported fatigue, sleep disturbance, excessive daytime sleepiness, and a majority of patients referred for a sleep consultation were diagnosed with obstructive sleep apnea (n = 33).

conclusionThe results highlight the promise of an interdisciplinary collaboration between dedicated a CRF clinic and sleep clinic to conduct effective assessments to identify treatable CRF and sleep disorders.

Indexed as

Disorders of Excessive SomnolenceNeoplasmsSleep Wake DisordersFatigueHumansPolysomnographyRetrospective StudiesSleepcancerCancer related fatiguepolysomnographysleep disordersleep disturbance

Identifiers

PMID34348178
PMCPMC8766868

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.