Observational studyPloS one2021
Post-stroke fatigue: A factor associated with inability to return to work in patients <60 years-A 1-year follow-up.
Observational study in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Experiences of support to return to work after stroke: longitudinal case studies from RETAKE trial.Health technology assessment (Winchester, England) · 2025Trial
- Poststroke Fatigue: An Overlooked Barrier to Functional Recovery.Journal of the American Heart Association · 2026Article
- The brain fatigue syndrome: a cross-diagnostic phenomenon.Frontiers in human neuroscience · 2026Article
- Trajectories of post-stroke fatigue and its influencing factors in young and middle-aged patients with intracerebral hemorrhage.Frontiers in neurology · 2026Article
- Physical Activity Interventions for Patients With Poststroke Fatigue: Protocol for a Scoping Review.JMIR research protocols · 2025Article
- Narrative Review on Post-Stroke Outcomes Through Recognition of Frailty, Sarcopenia, and Palliative Care Needs.Healthcare (Basel, Switzerland) · 2025Review
- Risk factors for post-stroke aspiration pneumonia in long-term hospitalized patients: a retrospective study.Journal of thoracic disease · 2025Article
- An investigation of post-stroke fatigue levels and influencing factors in young and middle-aged stroke patients: a cross-sectional study.Scientific reports · 2025Article
- Anxiety and depression one year after the first stroke among Lebanese survivors: proportions, changes, and predictors.BMC psychiatry · 2025Article
- A new mindfulness and psycho-educative program for treatment of brain fatigue, evaluated after an acquired brain injury and multiple sclerosis.Health psychology and behavioral medicine · 2025Article
- Exploring the usefulness of real-time digitally supported fatigue monitoring in fatigue management: Perspectives from occupational therapists and brain injury survivors.The British journal of occupational therapy · 2024Article
- Exploring the status and associated factors of the readiness for return-to-work in young and middle-aged stroke patients.Scientific reports · 2024Article
- The impact of post-stroke fatigue on inpatient rehabilitation outcomes: An observational study.PloS one · 2024Observational
- Early poststroke clinically significant fatigue predicts functional independence: a prospective longitudinal study.Frontiers in neurology · 2024Article
- Eccentric strengthening vs. conventional therapy in sub-acute stroke survivors: a randomized controlled trial.Frontiers in neurology · 2024Article
- Longitudinal Associations Between Higher Self-Reported Energy, Gait Speed, and Cognition in Older Adults With Fatigue.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Addressing mood and fatigue in return-to-work programmes after stroke: a systematic review.Frontiers in neurology · 2023Review
- Article
- A Mobile Phone Text Messaging Intervention to Manage Fatigue for People With Multiple Sclerosis, Spinal Cord Injury, and Stroke: Development and Usability Testing.JMIR formative research · 2022Article
- Fatigue 7 years post-stroke: Predictors and correlated features.Acta neurologica Scandinavica · 2022Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the association between post-stroke fatigue and inability to return to work/drive in young patients aged <60 years with first stroke who were employed prior to infarct while controlling for stroke severity, age, extent of disability, cognitive function, and depression. The Fatigue Severity Scale (FSS) was used to evaluate post-stroke fatigue in this 1-year prospective cohort study. Follow-ups were completed at 3, 6, and 12 months post rehabilitation discharge. A total of 112 patients were recruited, 7 were excluded, due to loss to follow-up (n = 6) and being palliative (n = 1), resulting in 105 participants (71% male, average age 49 ±10.63 years). Stroke patients receiving both inpatient and outpatient rehabilitation were consecutively recruited. Persistent fatigue remained associated with inability to return to work when controlling for other factors at 3 months (adjusted OR = 18, 95% CI: 2.9, 110.3, p = 0.002), 6 months (adjusted OR = 29.81, 95% CI: 1.7, 532.8, p = 0.021), and 12 months (adjusted OR = 31.6, 95% CI: 1.8, 545.0, p = 0.018). No association was found between persistent fatigue and return to driving. Fatigue at admission was associated with inability to return to work at 3 months but not return to drive. Persistent fatigue was found to be associated with inability to resume work but not driving. It may be beneficial to routinely screen post-stroke fatigue in rehabilitation and educate stroke survivors and employers on the impacts of post-stroke fatigue on return to work.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.