ArticleEnvironmental health perspectives2021
Fine Particulate Matter and Dementia Incidence in the Adult Changes in Thought Study.
Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A systematic review with a Burden of Proof meta-analysis of health effects of long-term ambient fine particulate matter (PMNature aging · 2025Pooled it
- Air pollution: a latent key driving force of dementia.BMC public health · 2024Pooled it
- Beneficial Effect of Societal Factors on APOE-ε2 and ε4 Carriers' Brain Health: A Systematic Review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Pooled it
- Ambient air pollution and clinical dementia: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2023Pooled it
- A critical review of potential modifiers of air pollutant associations with dementia and related outcomes.Neurotoxicology · 2026Review
- Integrating contextual determinants and polygenic risk to examine dementia and late-life cognition in the Multi-Ethnic Study of Atherosclerosis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Racial and ethnic differences in the impact of air pollution on the risk of Alzheimer's disease and related dementias in the Multiethnic Cohort Study.Environment international · 2026Article
- Dissecting the effect of long-term exposure to air pollution on risk of dementia in UK Biobank.Environmental health : a global access science source · 2025Article
- Air toxics and late-life dementia and cognitive impairment in Mexican Americans.Environmental research · 2025Article
- Ambient Air Pollution, Cognitive Impairment, and Dementia Among Older Patients Being Evaluated for Kidney Transplantation.Clinical transplantation · 2025Article
- Long-term exposure to air pollution and cognitive aging: Findings from a United States cohort of older adults.Journal of Alzheimer's disease : JAD · 2025Article
- Association of tailpipe-related and nontailpipe-related air pollution exposure with neuroimaging outcomes.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Traffic-related air pollutant exposure and physical performance in the Adult Changes in Thought cohort.Environment international · 2025Article
- 'It makes us sick': experiences of air pollution among children with asthma and their caregivers in African countries.IJTLD open · 2025Article
- Optimizing Air Pollution Exposure Assessment with Application to Cognitive Function.Research report (Health Effects Institute) · 2025Article
- Pathways to the Brain: Impact of Fine Particulate Matter Components on the Central Nervous System.Antioxidants (Basel, Switzerland) · 2025Review
- Ultrafine particles and late-life cognitive function: Influence of stationary mobile monitoring design on health inferences.Environmental pollution (Barking, Essex : 1987) · 2025Article
- Regional variability of the impact of cardiometabolic diseases on incident dementia in United States Medicare beneficiaries.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Ambient Air Pollution and Parkinson's Disease and Alzheimer's Disease: An Updated Meta-Analysis.Toxics · 2025Article
- Life-course exposure to air pollution and the risk of dementia in the Lothian Birth Cohort 1936.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
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11 authors.
Funding
Abstract
backgroundAir pollution may be associated with elevated dementia risk. Prior research has limitations that may affect reliability, and no studies have evaluated this question in a population-based cohort of men and women in the United States.
objectivesWe evaluated the association between time-varying, 10-y average fine particulate matter (
methodsUsing the Adult Changes in Thought (ACT) population-based prospective cohort study in Seattle, we linked spatiotemporal model-based
resultsWe report 1,136 cases of incident dementia among 4,166 individuals with nonmissing APOE status. Mean [mean ± standard deviation (SD)] 10-y average DISCUSSION: In this prospective cohort study with extensive exposure data and consensus-based outcome ascertainment, elevated long-term exposure to
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.