Evidence map›Paper›PMID 34347518›Full record

ArticleApplied and environmental microbiology2021

Adaptive Synthesis of a Rough Lipopolysaccharide in Geobacter sulfurreducens for Metal Reduction and Detoxification.

Morgen M Clark, Michael D Paxhia, Jenna M Young, Michael P Manzella, Gemma Reguera

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Species-Specific Stress Responses to Selenium Nanoparticles inNanomaterials (Basel, Switzerland) · 2025
    Article
  6. Applied and environmental microbiology · 2025
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Morgen M ClarkDepartment of Microbiology and Molecular Genetics, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA.
Michael D PaxhiaDepartment of Microbiology and Molecular Genetics, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA.
Jenna M YoungDepartment of Microbiology and Molecular Genetics, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA.
Michael P ManzellaDepartment of Microbiology and Molecular Genetics, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA.
Gemma RegueraDepartment of Microbiology and Molecular Genetics, Michigan State Universitygrid.17088.36, East Lansing, Michigan, USA.ORCID 0000-0003-4317-7933
Michigan State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of some metal-reducing bacteria to produce a rough (no O-antigen) lipopolysaccharide (LPS) could facilitate surface interactions with minerals and metal reduction. Consistent with this, the laboratory model metal reducer Geobacter sulfurreducens PCA produced two rough LPS isoforms (with or without a terminal methyl-quinovosamine sugar) when growing with the soluble electron acceptor fumarate but expressed only the shorter and more hydrophilic variant when reducing iron oxides. We reconstructed from genomic data conserved pathways for the synthesis of the rough LPS and generated heptosyltransferase mutants with partial (Δ

Indexed as

BiofilmsGeobacterLipopolysaccharidesOxidation-ReductionUraniumLipopolysaccharidesUraniumbiofilmscell envelopeelectromicrobiologyextracellular electron transfermetal reductionouter membrane vesiclestype IV pili

Identifiers

PMID34347518
PMCPMC8478458
OpenAlexW3188152244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.