Evidence map›Paper›PMID 34347517›Full record

ArticleApplied and environmental microbiology2021

Bacteriophage Treatment before Chemical Disinfection Can Enhance Removal of Plastic-Surface-Associated Pseudomonas aeruginosa.

Elyse Stachler, Anina Kull, Timothy R Julian

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. [Advances in Novel Disinfection Technologies for Biofilm-Associated Nosocomial Infections].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Environmental hygiene strategies to combat antimicrobial resistance in healthcare settings.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025
    Review
  14. Review
  15. Combined Effects of theMicroorganisms · 2024
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Elyse StachlerEawag, Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, Switzerland.ORCID 0000-0002-4961-1983
Anina KullEawag, Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, Switzerland.
Timothy R JulianEawag, Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, Switzerland.ORCID 0000-0003-1000-0306
Swiss Federal Institute of Aquatic Science and Technology · CHSwiss Tropical and Public Health Institute · CH

Funding

ETH | Eidgenössische Anstalt für Wasserversorgung Abwasserreinigung und Gewässerschutz (EAWAG)
6 · The paper itself

Abstract

Opportunistic pathogens can linger on surfaces in hospital and building plumbing environments, leading to infections in at-risk populations. Furthermore, biofilm-associated bacteria are protected from removal and inactivation protocols such as disinfection. Bacteriophages show promise as tools to treat antibiotic-resistant infections. As such, phages may also be useful in environmental applications to prevent newly acquired infections. In the current study, the potential of synergies between bacteriophage and chemical disinfection against the opportunistic pathogen Pseudomonas aeruginosa was assessed under various conditions. Specifically, surface-associated P. aeruginosa was treated with various concentrations of phages (P1 or JG004), chemical disinfectants (sodium hypochlorite or benzalkonium chloride), or combined sequential treatments under three distinct attachment models (spot inoculations, dry biofilms, and wet biofilms). Phages were very effective at removing bacteria in spot inoculations (>3.2 log

Indexed as

BacteriophagesBenzalkonium CompoundsBiofilmsDisinfectantsDisinfectionPlasticsPseudomonas aeruginosaSodium HypochloriteBenzalkonium CompoundsDisinfectantsPlasticsSodium Hypochloritebiofilmopportunistic pathogensphage therapy

Identifiers

PMID34347517
PMCPMC8478462
OpenAlexW3192634619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.