Evidence map›Paper›PMID 34347462›Full record

ArticleEnvironmental science & technology2021

Temporal Trends of Phenol, Paraben, and Triclocarban Exposure in California Pregnant Women during 2007-2014.

Kyunghoon Kim, Hyeong-Moo Shin, Stefanie A Busgang, Dana Boyd Barr, Parinya Panuwet, Rebecca J Schmidt, Irva Hertz-Picciotto, Deborah H Bennett

Open access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Review
  3. Bisphenol S and female reproductive toxicity: a scoping review of human studies.Journal of exposure science & environmental epidemiology · 2026
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  7. Review
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  10. nhanesA: achieving transparency and reproducibility in NHANES research.Database : the journal of biological databases and curation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Kyunghoon KimDepartment of Earth and Environmental Sciences, University of Texas, Arlington, Texas 76019, United States.
Hyeong-Moo ShinDepartment of Earth and Environmental Sciences, University of Texas, Arlington, Texas 76019, United States.ORCID 0000-0002-7001-2555
Stefanie A BusgangDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.
Dana Boyd BarrGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, United States.
Parinya PanuwetGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, United States.
Rebecca J SchmidtDepartment of Public Health Sciences, University of California, Davis (UC Davis), California 95616, United States.
Irva Hertz-PicciottoDepartment of Public Health Sciences, University of California, Davis (UC Davis), California 95616, United States.
Deborah H BennettDepartment of Public Health Sciences, University of California, Davis (UC Davis), California 95616, United States.ORCID 0000-0001-6698-2316
University of California, Davis · USEmory University · USThe University of Texas at Arlington · USIcahn School of Medicine at Mount Sinai · US

Funding

Statistical Services and Methods Development ResourceU2CES026555 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI TEITELBAUM, SUSAN L · 2015 to 2025
$26.4M
UC Davis Environmental Health Sciences Core CenterP30ES023513 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Ameer Taha · 2015 to 2026
$26.0M
WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J · 1985 to 2015
$25.2M
Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
Trajectories and Environments in Autism: a Multi-cohort Study (TEAMS) following autism families in ECHO Phase 2UH3OD023342 · OD · DREXEL UNIVERSITY · PI KRISTEN Lyall, HEATHER E VOLK · 2018 to 2026
$12.8M
UC Davis Center for Children's Environmental Health (CCEH)P01ES011269 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI VAN DE WATER, JUDY A. · 2001 to 2018
$12.5M
Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
Autism Risk, Prenatal Environmental Exposures, and Pathophysiologic MarkersR01ES020392 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HERTZ-PICCIOTTO, IRVA, OZONOFF, SALLY · 2011 to 2015
$9.0M
Rodent Behavior CoreU54HD079125 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HAGERMAN, RANDI J. · 2013 to 2019
$8.5M
National Exposure Assessment Laboratory at EmoryU2CES026560 · NIEHS · EMORY UNIVERSITY · PI MILLER, GARY W · 2015 to 2015
$8.3M
BUILDS MARBLES: Biorepository Upkeep and Infrastructure for Longitudinal Data Sharing for MARBLESR24ES028533 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Brittany D. Chambers Butcher, Rebecca Jean Schmidt · 2017 to 2026
$2.3M
Exposure to Perfluorinated Compounds and Risk for Autism Spectrum DisordersR21ES028131 · NIEHS · UNIVERSITY OF TEXAS ARLINGTON · PI SHIN, HYEONG-MOO · 2017 to 2018
$436k
NICHD NIH HHS P50 HD103526NICHD NIH HHS U54 HD079125NIEHS NIH HHS P01 ES011269NIEHS NIH HHS P30 ES019776NIEHS NIH HHS P30 ES023513NIEHS NIH HHS R01 ES020392NIEHS NIH HHS R21 ES025551NIEHS NIH HHS R21 ES028131NIEHS NIH HHS R24 ES028533NIEHS NIH HHS U2C ES026555NIEHS NIH HHS U2C ES026560NIH HHS UH3 OD023342
6 · The paper itself

Abstract

Little is known about temporal trends of pregnant women's exposures to environmental phenols and parabens. We quantified four phenols [bisphenol A (BPA), bisphenol F, bisphenol S, and triclosan), four parabens [butyl paraben, ethyl paraben (ETPB), methyl paraben (MEPB), and propyl paraben (PRPB)], and triclocarban in 760 urine samples collected during 2007-2014 from 218 California pregnant women participating in a high-familial risk autism spectrum disorder cohort. We applied multiple regression to compute least square geometric means of urinary concentrations and computed average annual percent changes. We compared our urinary concentrations with those of other study populations to examine geographic variations in pregnant women's exposure to these target compounds. Urinary concentrations of BPA, MEPB, ETPB, and PRPB in this study population decreased over the study period [percent change per year (95% confidence interval): -5.7% (-8.2%, -3.2%); -13.0% (-18.1%, -7.7%); -5.5% (-11.0%, 0.3%); and -13.3% (-18.3%, -8.1%), respectively] and were consistently lower than those in pregnant women in other U.S. regions during the same study period. In recent years, certain phenols and parabens with known adverse health effects are being regulated or replaced with alternatives, which explains decreased body burdens observed in this study population. Either the national regulations or the advocacy campaigns in California may have influenced exposures or consumer product choices.

Indexed as

Autism Spectrum DisorderParabensCarbanilidesEnvironmental ExposureFemaleHumansPhenolPhenolsPregnancyPregnant PeopleCarbanilidesParabensPhenolPhenolstriclocarbanbisphenolsgeographic variationspersonal care productsregulationssocial forcestemporal changes

Identifiers

PMID34347462
PMCPMC8405127
OpenAlexW3187417045

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.