ArticleCNS neuroscience & therapeutics2021
Altered mismatch response of inferior parietal lobule in amnestic mild cognitive impairment: A magnetoencephalographic study.
Article in CNS neuroscience & therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Potential Targets for Scalp Acupuncture and Brain Stimulation in Mental Disorders: Evidence From Large-Scale Meta-Analyses.Alpha psychiatry · 2026Pooled it
- The neurophysiology of healthy and pathological aging: a comprehensive systematic review.Brain structure & function · 2025Pooled it
- Baseline predictors of neurophysiological response to combined physical and cognitive training in older adults with subjective cognitive decline.BMC geriatrics · 2026Trial
- Effects of 6-Month Combined Physical Exercise and Cognitive Training on Neuropsychological and Neurophysiological Function in Older Adults with Subjective Cognitive Decline: A Randomized Controlled Trial.Journal of Alzheimer's disease : JAD · 2024Trial
- FREQ-NESS Reveals Age-Related Differences in Frequency-Resolved Brain Networks During Auditory Recognition and Resting State.Annals of the New York Academy of Sciences · 2026Article
- Alzheimer's disease and memantine effects on NMDA-receptor blockade: non-invasive in vivo insights from magnetoencephalography.Molecular psychiatry · 2026Article
- Alzheimer's disease and its progression reduce pyramidal cell gain and connectivity.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Research progress on brain network imaging biomarkers of subjective cognitive decline.Frontiers in neuroscience · 2025Review
- Altered functional brain network patterns in patients with migraine without aura after transcutaneous auricular vagus nerve stimulation.Scientific reports · 2023Article
- Alterations of voxel-wise spontaneous activity and corresponding brain functional networks in multiple system atrophy patients with mild cognitive impairment.Human brain mapping · 2023Article
- Development and validation of prediction models for neurocognitive disorders in adult patients admitted to the ICU with sleep disturbance.CNS neuroscience & therapeutics · 2022Article
- A Deep Spatiotemporal Attention Network for Mild Cognitive Impairment Identification.Frontiers in aging neuroscience · 2022Article
- Altered mismatch response of inferior parietal lobule in amnestic mild cognitive impairment: A magnetoencephalographic study.CNS neuroscience & therapeutics · 2021Article
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Abstract
backgroundMismatch negativity (MMN) reflects the functional integrity of sensory memory function. With the advantages of independence of individual's focused attention and behavioral cooperation, this neurophysiological signal is particularly suitable for investigating elderly with cognitive decline such as amnestic mild cognitive impairment (aMCI). However, the existing results remain substantially inconsistent whether these patients show deficits of MMN. In order to reconcile the previous disputes, the present study used magnetoencephalography combined with distributed source imaging methods to determine the source-level magnetic mismatch negativity (MMNm) in aMCI.
methodsA total of 26 healthy controls (HC) and 26 patients with aMCI underwent an auditory oddball paradigm during the MEG recordings. MMNm amplitudes and latencies in the bilateral superior temporal gyrus, inferior frontal gyrus, and inferior parietal lobule (IPL) were compared between HC and aMCI groups. The correlations of MMNm responses with performance of auditory/verbal memory tests were examined. Finally, MMNm and its combination with verbal/auditory memory tests were submitted to receiver operating characteristic (ROC) curve analysis.
resultsCompared to HC, patients with aMCI showed significantly delayed MMNm latencies in the IPL. Among the patients with aMCI, longer MMNm latencies of left IPL were associated with lower scores of Chinese Version Verbal Learning Test (CVVLT). The ROC curve analysis revealed that the combination of MMNm latencies of left IPL and CVVLT scores yielded a moderate accuracy in the discrimination of aMCI from HC at an individual level.
conclusionsOur data suggest dysfunctional MMNm in patients with aMCI, particularly in the IPL.
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