Evidence map›Paper›PMID 34346866›Full record

RevieweLife2021

The genomic consequences of hybridization.

Benjamin M Moran, Cheyenne Payne, Quinn Langdon, Daniel L Powell, Yaniv Brandvain, Molly Schumer

Open access · goldAbstract readReview
In one paragraph

Review in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  11. Evolution of genome-wide barriers to gene flow during complex speciation in rattlesnakes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  13. Review
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  15. Quantitative system drift.Proceedings of the National Academy of Sciences of the United States of America · 2026
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80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Benjamin M Moran *Department of Biology, Stanford University, Stanford, United States.ORCID 0000-0001-5230-0863
Cheyenne Payne *Department of Biology, Stanford University, Stanford, United States.ORCID 0000-0003-4651-3824
Quinn LangdonDepartment of Biology, Stanford University, Stanford, United States.
Daniel L PowellDepartment of Biology, Stanford University, Stanford, United States.ORCID 0000-0001-9204-645X
Yaniv BrandvainDepartment of Ecology, Evolution & Behavior and Plant and Microbial Biology, University of Minnesota, Minneapolis, United States.
Molly SchumerDepartment of Biology, Stanford University, Stanford, United States.ORCID 0000-0002-2075-5668
Centro de Investigaciones Cientifícas de las Huastecas 'Aguazarca' · MXHoward Hughes Medical Institute · USStanford University · USUniversity of Minnesota · US

Funding

The population genomics of hybridization: from genetic incompatibilities to genome evolutionR35GM133774 · NIGMS · STANFORD UNIVERSITY · PI Molly Schumer · 2019 to 2026
$3.3M
Howard Hughes Medical InstituteNIGMS NIH HHS R35 GM133774
6 · The paper itself

Abstract

In the past decade, advances in genome sequencing have allowed researchers to uncover the history of hybridization in diverse groups of species, including our own. Although the field has made impressive progress in documenting the extent of natural hybridization, both historical and recent, there are still many unanswered questions about its genetic and evolutionary consequences. Recent work has suggested that the outcomes of hybridization in the genome may be in part predictable, but many open questions about the nature of selection on hybrids and the biological variables that shape such selection have hampered progress in this area. We synthesize what is known about the mechanisms that drive changes in ancestry in the genome after hybridization, highlight major unresolved questions, and discuss their implications for the predictability of genome evolution after hybridization.

Indexed as

GenomeHybridization, GeneticGene FlowGenomicsGenotypeHumansadmixtureancestryevolutionary biologygeneticsgenomicshybridizationincompatibilityintrogressionselection

Identifiers

PMID34346866
PMCPMC8337078
OpenAlexW3112527437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.