ArticleAmerican journal of respiratory and critical care medicine2021
Obesity-related IL-18 Impairs T-Regulatory Cell Function and Promotes Lung Ischemia-Reperfusion Injury.
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In one paragraph
Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 40 citations in OpenAlex.
- CT-adipose measures identify severe SARS-CoV-2 risk beyond traditional obesity metrics: a C4R cohort study.BMC pulmonary medicine · 2026Article
- Recruitment of CCR5Genes and immunity · 2026Article
- Adaptive-like CAR-iPSC-CD4⁺ T cells outperform CD8⁺ counterparts in sustained ALL control.Inflammation and regeneration · 2026Article
- Correlation between immune suppressor cells and cytokines in the peripheral blood of patients with chronic lymphocytic leukemia.Frontiers in oncology · 2026Article
- HIF1α Attenuated the Lung Ischemia-Reperfusion Injury by Activating the miR-485/Notch1 Signalling.Journal of cellular and molecular medicine · 2026Article
- Treg dysregulation in the oxidative lung milieu: an emerging mechanistic link in interstitial lung disease associated with systemic autoimmune rheumatic diseases.Frontiers in immunology · 2026Review
- Effect of subcutaneous lidocaine-hydroxypropyl-β-cyclodextrin (HP-β-CD) on quality of life in patients with post-COVID condition: a 36-week observational interrupted time series study.EClinicalMedicine · 2025Article
- A Study on Prognostic Risk Factors of Cervical Spondylotic Myelopathy.Journal of Korean Neurosurgical Society · 2025Article
- An amphiregulin reporter mouse enables transcriptional and clonal expansion analysis of reparative lung Tregs.JCI insight · 2025Article
- Obesity-associated reduction of miR-150-5p in extracellular vesicles promotes ventilator-induced lung injury by modulating the lysosomal degradation of VE-cadherin.Cell death discovery · 2025Article
- Elevated GFI1 in Alveolar Macrophages Suppresses ACOD1 Expression and Exacerbates Lipopolysaccharide-Induced Lung Injury in Obesity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Advances in lung ischemia/reperfusion injury: unraveling the role of innate immunity.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024Review
- Th17/Treg balance: the bloom and wane in the pathophysiology of sepsis.Frontiers in immunology · 2024Review
- Biological and clinical roles of IL-18 in inflammatory diseases.Nature reviews. Rheumatology · 2024Review
- Mitigating the risk of inflammatory type primary graft dysfunction by applying an integrated approach to assess, modify and match risk factors in lung transplantation.Frontiers in transplantation · 2024Article
- The protective effect of carbamazepine on acute lung injury induced by hemorrhagic shock and resuscitation in rats.PloS one · 2024Article
- Pyroptosis: the potential eye of the storm in adult-onset Still's disease.Inflammopharmacology · 2023Review
- Associations between anthropometric parameters and immune-phenotypical characteristics of circulating Tregs and serum cytokines.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023Article
- Exploring the application of sildenafil for high-fat diet-induced erectile dysfunction based on interleukin-18-mediated NLRP3/Caspase-1 signaling pathway.Sexual medicine · 2023Article
- Body Mass Index and Cause-Specific Mortality after Lung Transplantation in the United States.Annals of the American Thoracic Society · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 6 institutions in 3 countries.
Tatiana AkimovaDivision of Transplant Immunology, Department of Pathology and Laboratory Medicine.ORCID 0000-0003-2767-8762
Tianyi ZhangDivision of Transplant Immunology, Department of Pathology and Laboratory Medicine.
Lanette M ChristensenDivision of Transplant Immunology, Department of Pathology and Laboratory Medicine.
Zhonglin WangDivision of Transplant Surgery and.
Rongxiang HanDivision of Transplant Immunology, Department of Pathology and Laboratory Medicine.
Dmitry NegorevDivision of Transplant Immunology, Department of Pathology and Laboratory Medicine.
Arabinda SamantaDivision of Transplant Immunology, Department of Pathology and Laboratory Medicine.
Isaac E SassonDepartment of Obstetrics and Gynecology, and.
Trivikram GaddaparaDepartment of Pediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Jing JiaoDivision of Nephrology.
Liqing WangDivision of Transplant Immunology, Department of Pathology and Laboratory Medicine.
Tricia R BhattiDivision of Transplant Immunology, Department of Pathology and Laboratory Medicine.
Matthew H LevineDivision of Transplant Surgery and.
Joshua M DiamondDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Ulf H BeierDivision of Nephrology.
Rebecca A SimmonsDepartment of Pediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Edward CantuDivision of Cardiovascular Surgery, Department of Surgery.
David S WilkesDivision of Pulmonary, Allergy, Critical Care, and Occupational Medicine, School of Medicine, and.
David J LedererDivision of Pulmonary, Allergy, and Critical Care Medicine, College of Physicians and Surgeons, Columbia University, New York, New York.
Michaela AndersonDivision of Pulmonary, Allergy, and Critical Care Medicine, College of Physicians and Surgeons, Columbia University, New York, New York.ORCID 0000-0001-9274-7643
Jason D ChristieDivision of Cardiovascular Surgery, Department of Surgery.ORCID 0000-0003-0519-218X
Wayne W HancockDivision of Transplant Immunology, Department of Pathology and Laboratory Medicine.ORCID 0000-0002-7211-5291
Center for Digestive and Liver Diseases · USChildren's Hospital of Philadelphia · USPulmonary and Allergy Associates · USColumbia University · USNHS Blood and Transplant · GBCardiovascular Research Center · BR
Funding
Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Trevor M Penning · 2006 to 2026
$35.3MLong Term Follow up of the Lung Transplant Outcomes Group CohortU01HL145435 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D, PALMER, SCOTT M · 2019 to 2025
$10.2MObesity, Inflammation, and Lung Injury After Lung TransplantationR01HL114626 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHRISTIE, JASON D, LEDERER, DAVID J. · 2013 to 2016
$3.1MLung Transplant Microbiome and Chronic Allograft DysfunctionR01HL113252 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI BUSHMAN, FREDERIC D, CHRISTIE, JASON D · 2013 to 2016
$2.9MHDAC2 Inhibition Mitigates Renal Ischemia Reperfusion InjuryR01DK106243 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LEVINE, MATTHEW HOWARD · 2016 to 2020
$1.8MPre-Transplant Monocyte HDAC6 Expression and Risk of Primary Graft Dysfunction in Clinical Lung Transplant RecipientsR01HL154241 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI HANCOCK, WAYNE WILLIAM · 2021 to 2024
$1.8MFoxp3+ Treg Cells & Primary Graft Dysfunction in Clinical Lung Tx RecipientsR01HL114468 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI HANCOCK, WAYNE WILLIAM · 2012 to 2015
$1.7MMentored Patient Oriented Research in Lung TransplantationK24HL115354 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2012 to 2021
$1.2MNHLBI NIH HHS K24 HL115354NHLBI NIH HHS R01 HL113252NHLBI NIH HHS R01 HL114468NHLBI NIH HHS R01 HL114626NHLBI NIH HHS R01 HL154241NHLBI NIH HHS U01 HL145435NIDDK NIH HHS R01 DK106243NIEHS NIH HHS P30 ES013508
Abstract
PubMed holds no abstract for this paper.
Indexed as
Acute Lung InjuryAdultAgedAged, 80 and overAnimalsFemaleHumansInterleukin-18Lung TransplantationMaleMiceMice, ObeseMiddle AgedObesityPrimary Graft DysfunctionReperfusion InjuryInterleukin-18IL-18lung transplantobesityprimary graft dysfunctionregulatory T cells
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.