Evidence map›Paper›PMID 34346265›Full record

SynthesisClimacteric : the journal of the International Menopause Society2022

Effect of menopausal symptom treatment options on palpitations: a systematic review.

Y Sheng, J S Carpenter, C D Elomba, J S Alwine, M Yue, C X Chen, J E Tisdale

Abstract readSystematic Review
In one paragraph

Synthesis in Climacteric : the journal of the International Menopause Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Y ShengSchool of Nursing, Indiana University, Indianapolis, IN, USA.ORCID 0000-0003-2311-3393
J S CarpenterSchool of Nursing, Indiana University, Indianapolis, IN, USA.ORCID 0000-0003-3988-8855
C D ElombaSchool of Nursing, Indiana University, Indianapolis, IN, USA.ORCID 0000-0001-9176-2702
J S AlwineSchool of Nursing, Indiana University, Indianapolis, IN, USA.ORCID 0000-0002-7140-6767
M YueCollege of Pharmacy, Purdue University, West Lafayette, IN, USA.
C X ChenSchool of Nursing, Indiana University, Indianapolis, IN, USA.ORCID 0000-0002-6902-1227
J E TisdaleCollege of Pharmacy, Purdue University, West Lafayette, IN, USA.ORCID 0000-0002-2117-9463

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Interdisciplinary Training in Cancer Prevention and ControlT32CA117865 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI Victoria Lee Champion, Catherine E Mosher · 2016 to 2026
$2.4M
NCATS NIH HHS UL1 TR002529NCI NIH HHS T32 CA117865
6 · The paper itself

Abstract

This systematic review provides an overview of the effects of menopausal symptom treatment options on palpitations, defined as feelings of missed or exaggerated heart beats, reported by perimenopausal and postmenopausal women. Guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, searches were conducted in PubMed, CINAHL and PsycINFO to identify articles meeting pre-specified inclusion criteria. Of 670 unique articles identified, 37 were included in the review. Treatments included drug therapies and non-drug therapies. Palpitations were studied as an outcome in 89% of articles and as an adverse effect in 11%. Articles provided mostly level II/III evidence due to their design and/or small sample sizes. Based on available evidence, no therapies can be fully recommended for clinical practice. Only some hormonal agents (e.g. estradiol) can be recommended with caution based on some positive evidence for reducing palpitation prevalence or severity. However, other drug therapies (e.g. moxonidine, atenolol), dietary supplementary treatments (e.g. isoflavones,

Indexed as

Cognitive Behavioral TherapyIsoflavonesFemaleHumansMenopauseIsoflavonesmenopausal symptomsMenopausal therapymenopausepalpitationsperimenopausepostmenopausesystematic review

Identifiers

PMID34346265
PMCPMC9710005

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.