Evidence map›Paper›PMID 34346188›Full record

ArticleESC heart failure2021

Combined evaluation of right ventricular function using echocardiography in non-ischaemic dilated cardiomyopathy.

Jumpei Ishiwata, Masao Daimon, Koki Nakanishi, Tadafumi Sugimoto, Takayuki Kawata, Tomohiro Shinozaki, Tomoko Nakao, Megumi Hirokawa, Naoko Sawada, Yuriko Yoshida and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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  11. The tricuspid annular plane systolic excursion/PASP ratio's accuracy and validity in assessing the right ventricular function: A narrative review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
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  18. Echocardiographic Advances in Dilated Cardiomyopathy.Journal of clinical medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Jumpei IshiwataDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Masao DaimonDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.ORCID 0000-0002-7616-3477
Koki NakanishiDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Tadafumi SugimotoDepartment of Clinical Laboratory, Mie University Hospital, Mie, Japan.
Takayuki KawataDepartment of Cardiovascular Medicine, Sassa General Hospital, Tokyo, Japan.
Tomohiro ShinozakiDepartment of Information and Computer Technology, Faculty of Engineering, Tokyo University of Science, Tokyo, Japan.
Tomoko NakaoDepartment of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, Japan.
Megumi HirokawaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Naoko SawadaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Yuriko YoshidaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Eisuke AmiyaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Masaru HatanoDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Hiroyuki MoritaDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Yutaka YatomiDepartment of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, Japan.
Issei KomuroDepartment of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
University of Tokyo Hospital · JPMie University Hospital · JPSasaki Institute · JPTokyo University of Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsAlthough comprehensive assessment of right ventricular (RV) function using multiple echocardiographic parameters is recommended for management of patients with non-ischaemic dilated cardiomyopathy (DCM), it is unclear which RV parameters to combine. Additionally, normalization of RV parameters by estimated pulmonary artery systolic pressure (PASP), in consideration of RV-pulmonary artery coupling, may be clinically significant. The aim of our study was to elucidate the best combination of echocardiographic RV functional parameters, with or without indexing for PASP, to predict outcome in patients with heart failure with reduced ejection fraction secondary to DCM. METHODS AND

resultsWe retrospectively analysed 109 DCM patients with left ventricular ejection fraction <40%. RV size was assessed by RV end-diastolic area (RVEDA) and RV end-systolic area (RVESA) from RV-focused apical four-chamber view. RV function was assessed by fractional area change (FAC) and tricuspid annular plane systolic excursion (TAPSE) and by RV longitudinal strain (RVLS) using two-dimensional speckle-tracking echocardiography. All functional parameters were also indexed for estimated PASP. Cox analyses were used to evaluate the association of RV morphology and functional parameters with 1 year outcome (composite of left ventricular assist device implantation and all-cause death). Area under the curve was used to compare prognostic values. Mean age was 44 ± 14 years, and 76 (69.7%) were men. Mean left ventricular ejection fraction was 21.9%, median RVEDA was 22.1 cm

conclusionsNormalizing echocardiographic RV parameters for PASP did not improve the prognostic values for our population. Meanwhile, combined evaluation of FAC and RVLS improved risk stratification in patients with heart failure with reduced ejection fraction secondary to DCM.

Indexed as

Cardiomyopathy, DilatedVentricular Dysfunction, RightAdultEchocardiographyHumansMaleMiddle AgedRetrospective StudiesStroke VolumeVentricular Function, LeftVentricular Function, RightDilated cardiomyopathyEchocardiographyPulmonary arteryRight ventricular functionSpeckle-tracking echocardiography

Identifiers

PMID34346188
PMCPMC8497345
OpenAlexW3192607285

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.