ArticleDiabetologia2021
Assessing the linear and non-linear association of HbA
Article in Diabetologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Proteomic Pathways Linking Type 2 Diabetes Genetic Clusters to Cardiovascular Diseases: A Network Mendelian Randomisation Study.Diabetes, obesity & metabolism · 2026Article
- Associations of the hs-CRP/HDL-C ratio with cardiovascular metabolic multimorbidity: a large cross-sectional study.Scientific reports · 2026Article
- Reflections on Binary Thresholds for Hypercholesterolemia and Hypertension.Journal of the American College of Cardiology · 2025Article
- Interplay between BMI, neutrophil, triglyceride and uric acid: a case-control study and bidirectional multivariate mendelian randomization analysis.Nutrition & metabolism · 2025Article
- Age-specific differences in association of glycosylated hemoglobin levels with the prevalence of cardiovascular diseases among nondiabetics: the National Health and Nutrition Examination Survey 2005-2018.BMC cardiovascular disorders · 2024Article
- A two-sample Mendelian randomization study explores metabolic profiling of different glycemic traits.Communications biology · 2024Article
- Association between hemoglobin A1c and abdominal aortic calcification: results from the National Health and Nutrition Examination Survey 2013-2014.BMC cardiovascular disorders · 2024Article
- Evaluating the role of non-alcoholic fatty liver disease in cardiovascular diseases and type 2 diabetes: a Mendelian randomization study in Europeans and East Asians.International journal of epidemiology · 2023Article
- Article
- Differentiating Associations of Glycemic Traits With Atherosclerotic and Thrombotic Outcomes: Mendelian Randomization Investigation.Diabetes · 2022Article
- Sex differences in the association of fasting glucose with HbA1c, and their consequences for mortality: A Mendelian randomization study.EBioMedicine · 2022Article
- Association of hemoglobin A1c with the incidence of hypertension: A large prospective study.Frontiers in endocrinology · 2022Article
- HemoglobinA1c Is a Risk Factor for Changes of Bone Mineral Density: A Mendelian Randomization Study.Frontiers in endocrinology · 2022Article
- Dissecting the mediating and moderating effects of depression on the associations between traits and coronary artery disease: A two-step Mendelian randomization and phenome-wide interaction study.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
aims/hypothesisWe aimed to evaluate whether genetically predicted HbA
methodsWe performed linear univariable, multivariable and non-linear Mendelian randomisation analyses in 373,571 white British participants (mean age 56.9) from the UK Biobank.
resultsIn univariable linear Mendelian randomisation analysis, a 1 mmol/mol increase in genetically predicted HbA CONCLUSIONS/
interpretationThe study suggests a detrimental effect of HbA
Indexed as
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34345974What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.