Evidence map›Paper›PMID 34345831›Full record

ArticleCurrent research in toxicology2020

Sex differences in renal handling of inorganic mercury in aged rats.

Elizabeth H Pittman, Nigel D'Souza, Taylor N Mathis, Lucy Joshee, Jennifer L Barkin, Christy C Bridges

Open access · goldAbstract read
In one paragraph

Article in Current research in toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elizabeth H PittmanDepartment of Basic Medical Sciences, Mercer University School of Medicine, Macon, GA, USA.
Nigel D'SouzaDepartment of Basic Medical Sciences, Mercer University School of Medicine, Macon, GA, USA.
Taylor N MathisDepartment of Basic Medical Sciences, Mercer University School of Medicine, Macon, GA, USA.
Lucy JosheeDepartment of Basic Medical Sciences, Mercer University School of Medicine, Macon, GA, USA.
Jennifer L BarkinDepartment of Community Medicine, Mercer University School of Medicine, Macon, GA, USA.
Christy C BridgesDepartment of Basic Medical Sciences, Mercer University School of Medicine, Macon, GA, USA.
Mercer University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sex of an individual/animal has been shown to play an important role in many biological processes. Furthermore, sex may also be a factor in the way environmental toxicants, such as heavy metals, are handled by organisms. However, the effect of sex on the handling and disposition of heavy metals, such as mercury (Hg), has not been shown. Aging has also been shown to be a factor in the accumulation of heavy metals in that older individuals tend to have higher burdens of these metals. Therefore, the purpose of the current study was to evaluate the effect of sex on the accumulation of mercury in aged animals. Aged male and female rats were injected intravenously with 0.5 μmol or 2.0 μmol·kg

Indexed as

AgingGenderKidneyMercury

Identifiers

PMID34345831
PMCPMC8320637
OpenAlexW3011742729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.