Evidence map›Paper›PMID 34345805›Full record

ArticleJAMIA open2021

Smart About Meds (SAM): a pilot randomized controlled trial of a mobile application to improve medication adherence following hospital discharge.

Bettina Habib, David Buckeridge, Melissa Bustillo, Santiago Nicolas Marquez, Manish Thakur, Thai Tran, Daniala L Weir, Robyn Tamblyn

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAMIA open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04676165 (Evaluation of a Mobile Application to Enhance Medication Management Following Hospital Discharge), which is not on this map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04676165 nacompletednot on this map

Evaluation of a Mobile Application to Enhance Medication Management Following Hospital Discharge

TypeinterventionalSponsorMcGill UniversityRan2019 to 2020Enrolled66ConditionsMedication Adherence, Mobile ApplicationArmsSmart About Meds (SAM)
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bettina HabibClinical and Health Informatics Research Group, McGill University, Montreal, Canada.
David BuckeridgeClinical and Health Informatics Research Group, McGill University, Montreal, Canada.
Melissa BustilloClinical and Health Informatics Research Group, McGill University, Montreal, Canada.
Santiago Nicolas MarquezClinical and Health Informatics Research Group, McGill University, Montreal, Canada.
Manish ThakurClinical and Health Informatics Research Group, McGill University, Montreal, Canada.
Thai TranClinical and Health Informatics Research Group, McGill University, Montreal, Canada.
Daniala L WeirClinical and Health Informatics Research Group, McGill University, Montreal, Canada.
Robyn TamblynClinical and Health Informatics Research Group, McGill University, Montreal, Canada.
McGill University · CAMcGill University Health Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objectives of this pilot study were (1) to assess the feasibility of a larger evaluation of Smart About Meds (SAM), a patient-centered medication management mobile application, and (2) to evaluate SAM's potential to improve outcomes of interest, including adherence to medication changes made at hospital discharge and the occurrence of adverse events. MATERIALS AND

methodsWe conducted a pilot randomized controlled trial among patients discharged from internal medicine units of an academic health center between June 2019 and March 2020. Block randomization was used to randomize patients to intervention (received access to SAM at discharge) or control (received usual care). Patients were followed for 30 days post-discharge, during which app use was recorded. Pharmacy claims data were used to measure adherence to medication changes made at discharge, and physician billing data were used to identify emergency department visits and hospital readmissions during follow-up.

resultsForty-nine patients were eligible for inclusion in the study at hospital discharge (23 intervention, 26 control). In the 30 days of post-discharge, 15 (65.2%) intervention patients used the SAM app. During this period, intervention patients adhered to a larger proportion of medication changes (83.7%) than control patients (77.8%), including newly prescribed medications (72.7% vs 61.7%) and dose changes (90.9% vs 81.8%). A smaller proportion of intervention patients (8.7%) were readmitted to hospital during follow-up than control patients (15.4%).

conclusionThe high uptake of SAM among intervention patients supports the feasibility of a larger trial. Results also suggest that SAM has the potential to enhance adherence to medication changes and reduce the risk of downstream adverse events. This hypothesis needs to be tested in a larger trial.

trial registrationClinicaltrials.gov, registration number NCT04676165.

Indexed as

adverse eventsmedication adherencemobile applicationpilot randomized controlled trial

Identifiers

PMID34345805
PMCPMC8325487
OpenAlexW3191558428

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.