Evidence map›Paper›PMID 34345629›Full record

ArticleERJ open research2021

Descriptive analysis of long COVID sequelae identified in a multidisciplinary clinic serving hospitalised and non-hospitalised patients.

Stine Johnsen, Stefan M Sattler, Kamilla Woznica Miskowiak, Keerthana Kunalan, Alan Victor, Lars Pedersen, Helle Frost Andreassen, Barbara Jolanta Jørgensen, Hanne Heebøll, Michael Brun Andersen and 6 more

Abstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  4. Post-COVID-19 dyspnoea and pulmonary imaging: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
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  12. Health-Related Quality of Life and Functional Status of Post-COVID-19 Patients.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Stine JohnsenDept of Respiratory Medicine, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-7823-3697
Stefan M SattlerDept of Respiratory Medicine, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.
Kamilla Woznica MiskowiakNeurocognition and Emotion in Affective Disorders, Copenhagen, Denmark.
Keerthana KunalanDept of Respiratory Medicine, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.
Alan VictorDept of Respiratory Medicine, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.
Lars PedersenDept of Respiratory Medicine, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-5950-652X
Helle Frost AndreassenDept of Respiratory Medicine, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.
Barbara Jolanta JørgensenDept of Radiology, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.
Hanne HeebøllDept of Radiology, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.
Michael Brun AndersenDept of Radiology, Copenhagen University Hospital at Herlev/Gentofte, Copenhagen, Denmark.
Lisbeth MarnerDept of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital at Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Carsten HædersdalDept of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital at Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Henrik HansenRespiratory Research Unit, Dept of Respiratory Medicine, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.
Sisse Bolm DitlevRespiratory Research Unit, Dept of Respiratory Medicine, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.
Celeste PorsbjergDept of Respiratory Medicine, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.
Thérèse S LapperreDept of Respiratory Medicine, Copenhagen University Hospital at Bispebjerg, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-5176-0101

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are emerging data of long-term effects of coronavirus disease 2019 (COVID-19) comprising a diversity of symptoms. The aim of this study was to systematically describe and measure pulmonary and extra-pulmonary post-COVID-19 complications in relation to acute COVID-19 severity.

methodsPatients attending a standard of care 3 months post-hospitalisation follow-up visit and those referred by their general practitioner because of persistent post-COVID-19 symptoms were included. Patients underwent symptomatic, quality of life, pulmonary (lung function and high-resolution computed tomography (HRCT)), cardiac (high-resolution ECG), physical (1-min sit and stand test (1-MSTST), handgrip strength, cardiopulmonary exercise testing (CPET)) and cognitive evaluations.

resultsAll 34 hospitalised and 22 out of 23 non-hospitalised patients had ≥1 complaint or abnormal finding at follow-up. Overall, 67% of patients were symptomatic (Medical Research Council (MRC) ≥2 or COPD assessment test (CAT) ≥10), with no difference between hospitalised

conclusionThree months after COVID-19 infection, patients were still symptomatic and demonstrated objective respiratory, functional, radiological and cognitive abnormalities, which were more prominent in hospitalised patients. Our study underlines the importance of multidimensional management strategies in these patients.

Identifiers

PMID34345629
PMCPMC8091683

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.