Evidence map›Paper›PMID 34345594›Full record

ArticleToxicology reports2021

Effect of gold nanoparticles (AuNPs) on isolated rat tracheal segments.

Daniel Alberto Maldonado-Ortega, Gabriela Navarro-Tovar, Gabriel Martínez-Castañón, Carmen Gonzalez

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daniel Alberto Maldonado-OrtegaFacultad de Ciencias Quimicas, Universidad Autonoma de San Luis Potosi, Manuel Nava 6, Zona Universitaria, 78210, San Luis Potosi, SLP, Mexico.
Gabriela Navarro-TovarFacultad de Ciencias Quimicas, Universidad Autonoma de San Luis Potosi, Manuel Nava 6, Zona Universitaria, 78210, San Luis Potosi, SLP, Mexico.
Gabriel Martínez-CastañónFacultad de Ciencias, Universidad Autonoma de San Luis Potosi, Parque Chapultepec 1570, 78210, San Luis Potosi, SLP, Mexico.
Carmen GonzalezFacultad de Ciencias Quimicas, Universidad Autonoma de San Luis Potosi, Manuel Nava 6, Zona Universitaria, 78210, San Luis Potosi, SLP, Mexico.
Autonomous University of San Luis Potosí · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The AuNPs have been used in biomedicine as therapeutic tools for cancer. However, its role in the context of respiratory physiology has been little studied. This study aimed to determine the impact of AuNPs on respiratory smooth muscle tone, using a model of isolated tracheal rings from female and male rats precontracted with acetylcholine (ACh). AuNPs exerted a contractile effect only in the concentration of 100 ug/ml. This contractile effect was not modified by gender. The possible mediator

Indexed as

AuNPsBiosafetyNitric oxideToxicityTrachea

Identifiers

PMID34345594
PMCPMC8319458
OpenAlexW3179010386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.