Evidence map›Paper›PMID 34345321›Full record

ArticleCanadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC

Pharmacist-led sedative-hypnotic deprescribing in team-based primary care practice.

Eric Lui, Kimberly Wintemute, Maria Muraca, Christine Truong, Rita Ha, Albert Kee Buhm Choe, Laura Michell, Joanne Laine-Gossin, Harvey Blankenstein, Stephanie Klein and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  9. Review
  10. The role of pharmacists in deprescribing benzodiazepines: A scoping review.Exploratory research in clinical and social pharmacy · 2023
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  11. Article
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  13. Impact of Specialized Clinics on Medications Deprescribing in Older Adults: A Pilot Study in Ambulatory Care Clinics in a Teaching Hospital.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Eric LuiNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.ORCID https://orcid.org/0000-0003-1529-2096
Kimberly WintemuteNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
Maria MuracaNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
Christine TruongNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.ORCID https://orcid.org/0000-0003-3470-1457
Rita HaNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
Albert Kee Buhm ChoeNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
Laura MichellNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
Joanne Laine-GossinNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
Harvey BlankensteinNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
Stephanie KleinNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
Dana MayerNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
Victor FederNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
Michelle GreiverNorth York Family Health Team, the North York General Hospital and the University of Toronto, Department of Family and Community Medicine, Toronto, Ontario.
University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSedative-hypnotic (SH) medications are often used to treat chronic insomnia, with potentially serious long-term side effects. The objective of this study is to evaluate an interprofessional SH deprescribing program within a community team-based, primary care practice, with or without cognitive behavioural therapy for insomnia (CBT-I).

methodsRetrospective chart review for patients referred to the team pharmacist for SH deprescribing from February 2016 to June 2019.

resultsA total of 121 patients were referred for SH deprescribing, with 111 (92%) patients who attempted deprescribing (average age 69, range 29-97 years) and 22 patients who also received CBT-I. Overall, 36 patients (32%) achieved complete abstinence, and another 36 patients (32%) reduced their dosage by ≥50%. For the 36 patients who achieved complete abstinence, 26 (72%) patients remained abstinent at 6 months (9 patients resumed using SH and 1 patient was lost to follow-up). The proportion of patients achieving complete abstinence or reduced dosage of ≥50% (successful tapering) was higher with CBT-I than without CBT-I but did not reach statistical significance (77% vs 62%,

conclusionAlmost two-thirds of patients participating in our pharmacist-led program were able to stop or taper their SH medications by ≥50%. The role of CBT-I in SH deprescribing remains to be further elucidated.

Identifiers

PMID34345321
PMCPMC8282922
OpenAlexW3168405335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.