Evidence map›Paper›PMID 34345161›Full record

ArticleCancer informatics2021

Bioinformatics Study of Sea Cucumber Peptides as Antibreast Cancer Through Inhibiting the Activity of Overexpressed Protein (EGFR, PI3K, AKT1, and CDK4).

Teresa Liliana Wargasetia, Hana Ratnawati, Nashi Widodo, Muhammad Hermawan Widyananda

Open access · goldAbstract read
In one paragraph

Article in Cancer informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Microstructure of Sea CucumberGels (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Article
  9. Meniran (RSC advances · 2025
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Teresa Liliana WargasetiaFaculty of Medicine, Maranatha Christian University, Bandung, Indonesia.ORCID https://orcid.org/0000-0002-3433-3300
Hana RatnawatiFaculty of Medicine, Maranatha Christian University, Bandung, Indonesia.
Nashi WidodoBiology Department, Faculty of Mathematics and Natural Sciences, The University of Brawijaya, Malang, Indonesia.
Muhammad Hermawan WidyanandaBiology Department, Faculty of Mathematics and Natural Sciences, The University of Brawijaya, Malang, Indonesia.
Maranatha Christian University · IDUniversity of Brawijaya · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most common type of cancer in women globally. The overexpressed proteins, including EGFR, PI3K, AKT1, and CDK4, have a role in the growth of breast cancer cells. The 3D peptide structure of sea cucumber

Indexed as

AKT1CDK4EGFRpeptidePI3KSea cucumbers

Identifiers

PMID34345161
PMCPMC8283226
OpenAlexW3178798393

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.