ArticleProceedings of SPIE--the International Society for Optical Engineering2021
Task-based assessment of binned and list-mode SPECT systems.
Article in Proceedings of SPIE--the International Society for Optical Engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 3 citations in OpenAlex.
- CTLESS: A scatter-window projection and deep learning-based transmission-less attenuation compensation method for myocardial perfusion SPECT.IEEE transactions on medical imaging · 2024Article
- Article
- Development and task-based evaluation of a scatter-window projection and deep learning-based transmission-less attenuation compensation method for myocardial perfusion SPECT.Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
- A physics and learning-based transmission-less attenuation compensation method for SPECT.Proceedings of SPIE--the International Society for Optical Engineering · 2021Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
In SPECT, list-mode (LM) format allows storing data at higher precision compared to binned data. There is significant interest in investigating whether this higher precision translates to improved performance on clinical tasks. Towards this goal, in this study, we quantitatively investigated whether processing data in LM format, and in particular, the energy attribute of the detected photon, provides improved performance on the task of absolute quantification of region-of-interest (ROI) uptake in comparison to processing the data in binned format. We conducted this evaluation study using a DaTscan brain SPECT acquisition protocol, conducted in the context of imaging patients with Parkinson's disease. This study was conducted with a synthetic phantom. A signal-known exactly/background-known-statistically (SKE/BKS) setup was considered. An ordered-subset expectation-maximization algorithm was used to reconstruct images from data acquired in LM format, including the scatter-window data, and including the energy attribute of each LM event. Using a realistic 2-D SPECT system simulation, quantification tasks were performed on the reconstructed images. The results demonstrated improved quantification performance when LM data was used compared to binning the attributes in all the conducted evaluation studies. Overall, we observed that LM data, including the energy attribute, yielded improved performance on absolute quantification tasks compared to binned data.
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Registered trials
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