Evidence map›Paper›PMID 34345018›Full record

ReviewNature reviews. Neuroscience2021

On the relationship between maps and domains in inferotemporal cortex.

Michael J Arcaro, Margaret S Livingstone

Abstract readReview
In one paragraph

Review in Nature reviews. Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Article
  2. Article
  3. The cortical scene processing network emerges in infancy, prior to independent navigation experience.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. The Emergence of Topography and Hemispheric Lateralization in High-Level Vision.Quarterly journal of experimental psychology (2006) · 2026
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Expansion of a conserved architecture drives the evolution of the primate visual cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael J ArcaroUniversity of Pennsylvania, Philadelphia, PA, USA.
Margaret S LivingstoneHarvard Medical School, Boston, MA, USA. mlivingstone@hms.harvard.edu.ORCID http://orcid.org/0000-0002-1950-0123

Funding

Viral ModuleP30EY012196 · NEI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Gabriel Kreiman · 1998 to 2026
$21.3M
Reverse Correlation Mapping in V2 and V4R01EY016187 · NEI · HARVARD MEDICAL SCHOOL · PI LIVINGSTONE, MARGARET S · 2006 to 2021
$7.9M
The normal development of inferotemporal cortexR01EY025670 · NEI · HARVARD MEDICAL SCHOOL · PI LIVINGSTONE, MARGARET S · 2015 to 2025
$5.7M
NEI NIH HHS P30 EY012196NEI NIH HHS R01 EY016187NEI NIH HHS R01 EY025670
6 · The paper itself

Abstract

How does the brain encode information about the environment? Decades of research have led to the pervasive notion that the object-processing pathway in primate cortex consists of multiple areas that are each specialized to process different object categories (such as faces, bodies, hands, non-face objects and scenes). The anatomical consistency and modularity of these regions have been interpreted as evidence that these regions are innately specialized. Here, we propose that ventral-stream modules do not represent clusters of circuits that each evolved to process some specific object category particularly important for survival, but instead reflect the effects of experience on a domain-general architecture that evolved to be able to adapt, within a lifetime, to its particular environment. Furthermore, we propose that the mechanisms underlying the development of domains are both evolutionarily old and universal across cortex. Topographic maps are fundamental, governing the development of specializations across systems, providing a framework for brain organization.

Indexed as

AnimalsBrain MappingHumansMacaca mulattaNeuronsPhotic StimulationTemporal LobeVisual PathwaysVisual Perception

Identifiers

PMID34345018
PMCPMC8865285

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.