Evidence map›Paper›PMID 34344909›Full record

ArticleScientific reports2021

Machine learning-based prediction of acute kidney injury after nephrectomy in patients with renal cell carcinoma.

Yeonhee Lee, Jiwon Ryu, Min Woo Kang, Kyung Ha Seo, Jayoun Kim, Jungyo Suh, Yong Chul Kim, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo and 6 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Yeonhee LeeDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, South Korea.
Jiwon RyuDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, South Korea.
Min Woo KangDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, South Korea.
Kyung Ha SeoMedical Research Collaborating Center, Seoul National University Hospital, Seoul, South Korea.
Jayoun KimMedical Research Collaborating Center, Seoul National University Hospital, Seoul, South Korea.
Jungyo SuhDepartment of Urology, Seoul National University College of Medicine, Seoul, South Korea.
Yong Chul KimDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, South Korea.
Dong Ki KimDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, South Korea.
Kook-Hwan OhDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, South Korea.
Kwon Wook JooDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, South Korea.
Yon Su KimDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, South Korea.
Chang Wook JeongDepartment of Urology, Seoul National University College of Medicine, Seoul, South Korea.
Sang Chul LeeDepartment of Urology, Seoul National University College of Medicine, Seoul, South Korea.
Cheol KwakDepartment of Urology, Seoul National University College of Medicine, Seoul, South Korea. mdrafael@snu.ac.kr.
Sejoong KimDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, South Korea. sejoong2@snu.ac.kr.
Seung Seok HanDepartment of Internal Medicine, Seoul National University College of Medicine, 103 Daehakro, Jongno-gu, Seoul, 03080, South Korea. hansway80@gmail.com.
Seoul National University · KRSeoul National University Hospital · KRSeoul National University Bundang Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The precise prediction of acute kidney injury (AKI) after nephrectomy for renal cell carcinoma (RCC) is an important issue because of its relationship with subsequent kidney dysfunction and high mortality. Herein we addressed whether machine learning (ML) algorithms could predict postoperative AKI risk better than conventional logistic regression (LR) models. A total of 4104 RCC patients who had undergone unilateral nephrectomy from January 2003 to December 2017 were reviewed. ML models such as support vector machine, random forest, extreme gradient boosting, and light gradient boosting machine (LightGBM) were developed, and their performance based on the area under the receiver operating characteristic curve, accuracy, and F1 score was compared with that of the LR-based scoring model. Postoperative AKI developed in 1167 patients (28.4%). All the ML models had higher performance index values than the LR-based scoring model. Among them, the LightGBM model had the highest value of 0.810 (0.783-0.837). The decision curve analysis demonstrated a greater net benefit of the ML models than the LR-based scoring model over all the ranges of threshold probabilities. The application of ML algorithms improves the predictability of AKI after nephrectomy for RCC, and these models perform better than conventional LR-based models.

Indexed as

Machine LearningPostoperative ComplicationsAcute Kidney InjuryAdultAgedAlgorithmsCarcinoma, Renal CellDecision Making, Computer-AssistedFemaleHumansKidney NeoplasmsLogistic ModelsMaleMiddle AgedNephrectomyPrognosis

Identifiers

PMID34344909
PMCPMC8333365
OpenAlexW3188505891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.