Evidence map›Paper›PMID 34344816›Full record

ArticleSaudi medical journal2021

Effectiveness of using tranexamic acid in total hip and total knee arthroplasty: Single tertiary center experience.

Khalid Al Sheikh, Ali AlHandi, Abrar Bin Dohaim, Khawlah Ateeq, Khalid AlAqeely

Open access · diamondAbstract read
In one paragraph

Article in Saudi medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. A comparative study on hemostasis effect of different application methods and time of tranexamic acid in total hip arthroplasty.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Trial
  2. One Dose Versus Two Doses of Intravenous Tranexamic Acid in Revision Total Joint Arthroplasty.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Khalid Al SheikhFrom the College of Medicine (Al Sheikh) Assistant Professor, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Orthopedics, Department of Surgery, (Al Sheikh, AlHandi, Ateeq, AlAqeely) King Abdulaziz Medical City, Ministry of National Guard Health Affairs; from the College of Medicine (Bin Dohaim), King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabiaand from King Abdullah International Medical Research Center, Riyadh City, Saudi Arabia.
Ali AlHandiFrom the College of Medicine (Al Sheikh) Assistant Professor, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Orthopedics, Department of Surgery, (Al Sheikh, AlHandi, Ateeq, AlAqeely) King Abdulaziz Medical City, Ministry of National Guard Health Affairs; from the College of Medicine (Bin Dohaim), King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabiaand from King Abdullah International Medical Research Center, Riyadh City, Saudi Arabia.
Abrar Bin DohaimFrom the College of Medicine (Al Sheikh) Assistant Professor, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Orthopedics, Department of Surgery, (Al Sheikh, AlHandi, Ateeq, AlAqeely) King Abdulaziz Medical City, Ministry of National Guard Health Affairs; from the College of Medicine (Bin Dohaim), King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabiaand from King Abdullah International Medical Research Center, Riyadh City, Saudi Arabia.
Khawlah AteeqFrom the College of Medicine (Al Sheikh) Assistant Professor, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Orthopedics, Department of Surgery, (Al Sheikh, AlHandi, Ateeq, AlAqeely) King Abdulaziz Medical City, Ministry of National Guard Health Affairs; from the College of Medicine (Bin Dohaim), King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabiaand from King Abdullah International Medical Research Center, Riyadh City, Saudi Arabia.
Khalid AlAqeelyFrom the College of Medicine (Al Sheikh) Assistant Professor, King Saud Bin Abdulaziz University for Health Sciences; from the Division of Orthopedics, Department of Surgery, (Al Sheikh, AlHandi, Ateeq, AlAqeely) King Abdulaziz Medical City, Ministry of National Guard Health Affairs; from the College of Medicine (Bin Dohaim), King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabiaand from King Abdullah International Medical Research Center, Riyadh City, Saudi Arabia.
King Abdulaziz Medical City · SAKing Saud bin Abdulaziz University for Health Sciences · SANational Guard Health Affairs · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo measure the effectiveness of tranexamic acid (TXA); in total joint arthroplastyin terms of reducing post-operative blood loss.

methodsA retrospective cohort study in which patients who had underwent total hip arthroplasty (THA) and TKA between 2010-2018 in a single tertiary center. Those had received TXA (group 1) and those who had received no-TXA (group 2) were evaluated. Unpaired student's t-test was used to compare TXA and no-TXA groups for continuous variables and Chi-square test was used for categorical variables. A

resultsA total of 385 patients were included, 180 patients received TXA, and 205 patients received no-TXA. Post-operative blood loss was significantly less in TXA group (13.41±9.51,

conclusionTranexamic acid use in TKA and THA is effective in reducing post-operative blood loss in terms of drop in Hg level, total drainage output and blood transfusion rate.

Indexed as

Antifibrinolytic AgentsArthroplasty, Replacement, HipArthroplasty, Replacement, KneeTranexamic AcidBlood Loss, SurgicalHumansRetrospective StudiesAntifibrinolytic AgentsTranexamic Acidtotal hip arthroplastytotal knee arthroplastytranexamic acid

Identifiers

PMID34344816
PMCPMC9195556
OpenAlexW3188348168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.