Evidence map›Paper›PMID 34344722›Full record

ArticleOpen heart2021

Characteristics of infective endocarditis in a cancer population.

Cullen Grable, Syed W Yusuf, Juhee Song, George M Viola, Owais Ulhaq, Jose Banchs, Corey T Jensen, Harsh Goel, Saamir A Hassan

Erratum issuedOpen access · goldAbstract readComparative Study
In one paragraph

Article in Open heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Novel Diagnostic Methods for Infective Endocarditis.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Editorial: Cardio-oncology: mechanisms and therapeutics.Frontiers in cardiovascular medicine · 2023
    Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cullen GrableDepartment of Cardiology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Syed W YusufDepartment of Cardiology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Juhee SongDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
George M ViolaDepartment of Infectious Diseases, Infection Control and Employee Health, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, Houston, Texas, USA.
Owais UlhaqDepartment of Cardiology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Jose BanchsDepartment of Cardiology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0001-7375-2666
Corey T JensenDepartment of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Harsh GoelDepartment of Cardiology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Saamir A HassanDepartment of Cardiology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA SAHassan1@mdanderson.org.ORCID 0000-0002-3833-4618
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

backgroundInfective endocarditis (IE) is more common in patients with cancer as compared with the general population. Due to an immunocompromised state, the need for invasive procedures, hypercoagulability and the presence of indwelling catheters, patients with cancer are particularly predisposed to the development of IE.

objectivesLimited information exists about IE in patients with cancer. We aimed to evaluate the characteristics of patients with cancer and IE at our tertiary care centre, including a comparison of the microorganisms implicated and their association with mortality.

methodsA retrospective chart review of patients with cancer who had echocardiography for suspicion of endocarditis was conducted. A total of 56 patients with a confirmed diagnosis of cancer and endocarditis, based on the modified Duke criteria, were included in the study. Baseline demographics, risk factors for developing IE, echocardiography findings, microbiology and mortality data were analysed.

resultsFollowing the findings of vegetations by echocardiography, the median survival time was 8.5 months.

conclusionsOverall survival of patients with cancer and endocarditis is poor, with a worse outcome in patients with SAE.

Indexed as

Catheters, IndwellingEchocardiographyEndocarditisFemaleFollow-Up StudiesHumansImmunocompromised HostIncidenceMaleMiddle AgedNeoplasmsRetrospective StudiesRisk FactorsStaphylococcal InfectionsStaphylococcus aureusSurvival Rateendocarditisepidemiologyinfection

Identifiers

PMID34344722
PMCPMC8336187
OpenAlexW3190848676

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.