Evidence map›Paper›PMID 34344481›Full record

ArticleTropical diseases, travel medicine and vaccines2021

Gallbladder Wall Thickening associated with Dengue Shock Syndrome in a German traveller - no indication for surgical therapy - a case report.

Noemi F Freise, Björn Jensen, Verena Keitel, Tom Luedde

Open access · goldAbstract read
In one paragraph

Article in Tropical diseases, travel medicine and vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Acute acalculous cholecystitis and dengue fever: a case report from Australia.International journal of surgery case reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Noemi F FreiseDepartment of Gastroenterology, Hepatology and Infectious Diseases, Duesseldorf University Hospital, Heinrich-Heine-University, Moorenstr. 5, 40225, Duesseldorf, Germany. noemi.freise@med.uni-duesseldorf.de.ORCID http://orcid.org/0000-0002-1073-1793
Björn JensenDepartment of Gastroenterology, Hepatology and Infectious Diseases, Duesseldorf University Hospital, Heinrich-Heine-University, Moorenstr. 5, 40225, Duesseldorf, Germany.
Verena KeitelDepartment of Gastroenterology, Hepatology and Infectious Diseases, Duesseldorf University Hospital, Heinrich-Heine-University, Moorenstr. 5, 40225, Duesseldorf, Germany.
Tom LueddeDepartment of Gastroenterology, Hepatology and Infectious Diseases, Duesseldorf University Hospital, Heinrich-Heine-University, Moorenstr. 5, 40225, Duesseldorf, Germany.
Düsseldorf University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the increasing number of dengue virus infections imported into Germany, knowledge about the different phases of the disease and possible complications is essential for the treatment of patients. The virus is endemic in the tropics and subtropics and up to 2.5 billion people are at risk of infection. CASE PRESENTATION: Here we present a German traveller with dengue shock syndrome after returning from Thailand. After hospitalization the patient developed acute upper abdominal pain. The ultrasound findings were consistent with an acute acalculous cholecystitis, but were interpreted as dengue associated gallbladder wall thickening (GBWT). Therefore a surgical intervention was not indicated and would have been associated with an higher risk of complications in this situation. Under supportive care spontaneous regression of GBWT could be documented by sonography four days later as well as complete resolution of clinical symptoms.

conclusionGBWT in dengue virus infection mimicking acute cholecystitis is a differential diagnosis one should take into consideration in travellers returning from endemic areas and should be managed conservatively because of an high risk of bleeding and increased mortality under surgical therapy.

Indexed as

Acalculous cholecystitisCapillary leakageDengue shock syndromeGallbladder Wall thickening

Identifiers

PMID34344481
PMCPMC8336325
OpenAlexW3192268990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.