Evidence map›Paper›PMID 34344394›Full record

ReviewChinese medicine2021

Traditional Chinese Medicine in nonalcoholic fatty liver disease: molecular insights and therapeutic perspectives.

Xianmin Dai, Jiayi Feng, Yi Chen, Si Huang, Xiaofei Shi, Xia Liu, Yang Sun

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Chinese medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07676032 (The Impact of Body Composition on Setup Errors in Patients Undergoing Radiotherapy With Thermoplastic Mask Immobilization), which is not on this map. Cited by 56 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 6 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07676032 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Impact of Body Composition on Setup Errors in Patients Undergoing Radiotherapy With Thermoplastic Mask Immobilization: A Single-Center Prospective Cohort Study

Typeobservational_patient_registrySponsorShijiazhuang People's HospitalRan2026 to 2027Enrolled150ConditionsMalignant Neoplasms
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 6 syntheses or guidelines pooled it, 87 citations in OpenAlex.

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  11. International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xianmin Dai *Department of Clinical Pharmacy, Second Military Medical University/Naval Medical University, 200433, Shanghai, China.
Jiayi Feng *Department of Clinical Pharmacy, Second Military Medical University/Naval Medical University, 200433, Shanghai, China.
Yi ChenDepartment of Clinical Pharmacy, Second Military Medical University/Naval Medical University, 200433, Shanghai, China.
Si HuangDepartment of Clinical Pharmacy, Second Military Medical University/Naval Medical University, 200433, Shanghai, China.
Xiaofei ShiDepartment of Clinical Pharmacy, Second Military Medical University/Naval Medical University, 200433, Shanghai, China.
Xia LiuDepartment of Clinical Pharmacy, Second Military Medical University/Naval Medical University, 200433, Shanghai, China. lxflying@aliyun.com.
Yang SunDepartment of Clinical Pharmacy, Second Military Medical University/Naval Medical University, 200433, Shanghai, China. DawnySun@126.com.
Second Military Medical University · CN

Funding

Collaborative Innovation Center for Water Treatment Technology and Materials 20S11902700Collaborative Innovation Center for Water Treatment Technology and Materials 20ZR1470100National Natural Science Foundation of China 82073907
6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) has become the world's largest chronic liver disease, while there is still no specific drug to treat NAFLD. Traditional Chinese Medicine (TCM) have been widely used in hepatic diseases for centuries in Asia, and TCM's holistic concept and differentiation treatment of NAFLD show their advantages in the treatment of this complex metabolic disease. However, the multi-compounds and multi-targets are big obstacle for the study of TCM. Here, we summarize the pharmacological actions of active ingredients from frequently used single herbs in TCM compounds. The combined mechanism of herbs in TCM compounds are further discussed to explore their comprehensive effects on NAFLD. This article aims to summarize multiple functions and find the common ground for TCM treatment on NAFLD, thus providing enrichment to the scientific connotation of TCM theories and promotes the exploration of TCM therapies on NAFLD.

Indexed as

MechanismNAFLDSingle herbTCMTCM compound

Identifiers

PMID34344394
PMCPMC8330116
OpenAlexW3188070226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.