Evidence map›Paper›PMID 34344393›Full record

ArticleImplementation science : IS2021

Pharmacist dispensing of the abortion pill in Canada: Diffusion of Innovation meets integrated knowledge translation.

Sarah Munro, Kate Wahl, Judith A Soon, Edith Guilbert, Elizabeth S Wilcox, Genevieve Leduc-Robert, Nadra Ansari, Courtney Devane, Wendy V Norman

Abstract read
In one paragraph

Article in Implementation science : IS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah MunroCentre for Health Evaluation and Outcome Sciences, Providence Health Care Research Institute, Vancouver, British Columbia, Canada. sarah.munro@ubc.ca.ORCID 0000-0002-3884-6592
Kate WahlDepartment of Obstetrics & Gynaecology, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Judith A SoonFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Edith GuilbertDepartment of Obstetrics, Gynaecology and Reproduction, Laval University, Quebec City, Quebec, Canada.
Elizabeth S WilcoxSchool of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada.
Genevieve Leduc-RobertFaculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Nadra AnsariFaculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
Courtney DevaneSchool of Nursing, University of British Columbia, Vancouver, British Columbia, Canada.
Wendy V NormanDepartment of Family Practice, University of British Columbia, Vancouver, British Columbia, Canada.

Funding

CIHR CPP-329455-107837CIHR PHE148161Michael Smith Foundation for Health Research 16603Michael Smith Foundation for Health Research 16743Michael Smith Foundation for Health Research 18270Michael Smith Foundation for Health Research 2012-5139 [HSR]Society of Family Planning SFPRF11-19
6 · The paper itself

Abstract

backgroundSince Canadian drug regulatory approval of mifepristone for medical abortion in 2015 and its market availability in January 2017, the role of pharmacists in abortion provision has changed rapidly. We sought to identify the factors that influenced the initiation and provision of medical abortion from the perspectives of Canadian pharmacists, bridging two frameworks - Diffusion of Innovation in Health Service Organizations and integrated knowledge translation.

methodsWe conducted one-on-one semi-structured interviews with pharmacists residing in Canada who intended to stock and dispense mifepristone within the first year of availability. Our data collection, analysis, and interpretation were guided by reflexive thematic analysis and supported by an integrated knowledge translation partnership with pharmacy stakeholders.

resultsWe completed interviews with 24 participants from across Canada: 33% had stocked and 21% had dispensed mifepristone. We found that pharmacists were willing and able to integrate medical abortion care into their practice and that those who had initiated practice were satisfied with their dispensing experience. Our analysis indicated that several key Diffusion of Innovation constructs impacted the uptake of mifepristone, including: innovation (relative advantage, complexity and compatibility, technical support), system readiness (innovation-system fit, dedicated time, resources), diffusion and dissemination (expert opinion, boundary spanners, champions, social networks, peer opinions), implementation (external collaboration), and linkage. Participants' experiences suggest that integrated knowledge translation facilitated evidence-based changes to mifepristone dispensing restrictions, and communication of those changes to front line pharmacists.

conclusionsWe illustrate how Diffusion of Innovation and integrated knowledge translation may work together as complimentary frameworks for implementation science research. Unlike in the USA, UK, and other highly regulated settings globally, pharmacists in Canada are permitted to dispense mifepristone for medical abortion. We contribute to literature that shows that mifepristone dispensed outside of hospitals, clinics, and medical offices is safe and acceptable to both patients and prescribers. This finding is of particular importance to the current COVID-19 pandemic response and calls for continued and equitable access to abortion care in primary practice.

Indexed as

Diffusion of InnovationAbortifacient Agents, SteroidalAbortion, InducedCanadaFemaleHumansInterviews as TopicMifepristonePharmacistsPregnancyTranslational Research, BiomedicalAbortifacient Agents, SteroidalMifepristoneAbortion, inducedCanadaDiffusion of InnovationMifepristonePharmacistsPrimary Health Care

Identifiers

PMID34344393
PMCPMC8330203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.