ArticleBMC medicine2021
Differential effect of pre-pregnancy low BMI on fetal macrosomia: a population-based cohort study.
Article in BMC medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Association Between First-Trimester Gestational Weight Gain and the Risks of Gestational Diabetes Mellitus and Macrosomia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Article
- Pre-pregnancy body mass index and risk of macrosomia: glycemic status-specific thresholds and subgroup interactions in a prospective cohort.Frontiers in nutrition · 2025Article
- The association of maternal pre-pregnancy body mass index with macrosomia: a birth cohort study from China.PeerJ · 2025Article
- Gestational diabetes-combined excess weight gain exacerbates gut microbiota dysbiosis in newborns, associated with reduced abundance ofFrontiers in cellular and infection microbiology · 2024Article
- Refining the diagnosis of gestational diabetes mellitus: a systematic review and meta-analysis.Communications medicine · 2023Article
- Prevalence, risk factors, and consequences of hypothyroidism among pregnant women in the health region of Lleida: A cohort study.PloS one · 2023Observational
- The Nonlinear Relationship Between Body Mass Index (BMI) and Perceived Depression in the Chinese Population.Psychology research and behavior management · 2023Article
- Umbilical Cord Biometry and Fetal Abdominal Skinfold Assessment as Potential Biomarkers for Fetal Macrosomia in a Gestational Diabetes Romanian Cohort.Medicina (Kaunas, Lithuania) · 2022Article
- Risk Factors for Macrosomia in Multipara: A Multi-Center Retrospective Study.Children (Basel, Switzerland) · 2022Article
- Analytical Comparison of Risk Prediction Models for the Onset of Macrosomia Based on Three Statistical Methods.Disease markers · 2022Article
- Protective Effect of Maternal First-Trimester Low Body Mass Index Against Macrosomia: A 10-Year Cross-Sectional Study.Frontiers in endocrinology · 2022Article
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe differential effect of pre-pregnancy low BMI on macrosomia has not been fully addressed. Herein, we conducted a city-wide population-based cohort study to illuminate the association between pre-pregnancy low BMI and macrosomia, stratifying by maternal age, parity, and GDM status.
methodsAll pregnant women who paid their first prenatal visit to the hospital in Qingdao during August 1, 2018, to June 30, 2020, were recruited to this study. The interactive effect of maternal age and pre-pregnancy low BMI on macrosomia was evaluated using logistic regression models, followed by strata-specific analyses.
resultsA total of 105,768 mother-child pairs were included, and the proportion of fetal macrosomia was 11.66%. The interactive effect of maternal pre-pregnancy BMI and age was statistically significant on macrosomia irrespective of parity (nullipara: P
conclusionsMaternal low BMI is inversely associated with macrosomia irrespective of maternal age and parity. The impact of pre-pregnancy low BMI on macrosomia varied by maternal age and parity. The protective effect of a lower maternal BMI against fetal macrosomia was more prominent in nulliparous mothers aged 35 years and above, whereas multiparous mothers younger than 25 years of age were more benefited.
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