Evidence map›Paper›PMID 34344330›Full record

ArticleBMC surgery2021

Conspicuousness and recurrence related factors of ultrasound-guided microwave ablation in the treatment of benign thyroid nodules.

Baoying Xia, Boyang Yu, Xiaofei Wang, Yu Ma, Feng Liu, Yanping Gong, Xiuhe Zou, Jianyong Lei, Anping Su, Tao Wei and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Baoying Xia *Department of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Boyang Yu *Department of Ultrasound, West China Hospital, Sichuan University, Chengdu, 610041, China.
Xiaofei WangDepartment of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Yu MaDepartment of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Feng LiuDepartment of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Yanping GongDepartment of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Xiuhe ZouDepartment of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jianyong LeiDepartment of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Anping SuDepartment of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Tao WeiDepartment of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Jingqiang ZhuDepartment of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Qiang LuDepartment of Ultrasound, West China Hospital, Sichuan University, Chengdu, 610041, China. wsluqiang@126.com.
Zhihui LiDepartment of Thyroid, Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, 610041, China. rockoliver@vip.sina.com.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMicrowave ablation (MWA) is a minimally invasive technique for the treatment of benign thyroid nodules. The purpose of this study was to evaluate efficacy and safety of ultrasound-guided MWA in the treatment of benign thyroid nodules, and to find out the recurrence related factors, so as to provide reference for future clinical work.

methodsThis study retrospectively analyzed the patients who received ultrasound-guided MWA for benign thyroid nodules in our hospital from October 2018 to March 2020. A total of 214 patients were included in the study. We assessed thyroid volume changes (represented by volume reduction ratio VRR), the energy per 1 mL reduction in nodular volume (represented by energy volume ratio ΔE), the serum levels of free triiodide thyroid hormone (FT3), free thyroxine (FT4), thyrotropin (TSH) and complications after MWA treatment.

resultsThere were a total of 306 nodules in 214 patients, including 183 (85.51%) females and 31 (14.49%) males. The median diameter and volume of the nodule were 33 mm and 8.01 mL. The VRR at 1 month, 3 months, 6 months and 12 months were 40.79%, 60.37%, 74.59% and 85.60%, respectively. In addition, MWA had a better ablation effect for small nodules (initial volume ≤ 10 mL). In recurrent studies, we found that ΔE was an independent risk factor for benign thyroid nodules (P < 0.05).

conclusionsUltrasound-guided MWA is effective and safe in the treatment of benign thyroid nodules. In addition, it has little damage to surrounding tissues and no effect on thyroid function. Especially, the nodules with smaller initial volume, the treatment is better. On the other hand, the energy per 1 mL reduction ΔE in nodular volume may be associated with nodular recurrence, which requires further follow-up for longer periods. At this stage, we consider that ultrasound-guided MWA can be used as one of the main clinical treatment methods for benign thyroid nodules.

Indexed as

Catheter AblationThyroid NoduleFemaleHumansMaleMicrowavesNeoplasm Recurrence, LocalRetrospective StudiesTreatment OutcomeUltrasonography, InterventionalInitial volumeMicrowave ablationRecurrenceThyroid noduleVolume reduction ratio

Identifiers

PMID34344330
PMCPMC8336359
OpenAlexW3189349542

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.