Evidence map›Paper›PMID 34344324›Full record

ArticleBMC infectious diseases2021

Empyema necessitans with osteomyelitis of fifth rib due to Nocardia farcinica: a case report.

Swapnil Tripathi, Durga Shankar Meena, Amit Kumar Rohila, Neetha T R, Vidhi Jain, Deepak Kumar, Taruna Yadav, Mahendra Kumar Garg

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Multiple Deep Abscesses Caused by DisseminatedInfection and drug resistance · 2026
    Article
  2. Pathogens (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Lumpy jaw caused by Nocardia farcinica in a Holstein cow.Veterinary medicine and science · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Abdominal Abscesses Caused byInfection and drug resistance · 2023
    Article
  9. Diagnosis of Rare Bone Infection Caused byInfection and drug resistance · 2023
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Swapnil TripathiDepartment of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005, India.
Durga Shankar MeenaDepartment of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005, India. dsmims14@gmail.com.ORCID http://orcid.org/0000-0001-9524-5278
Amit Kumar RohilaDepartment of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005, India.
Neetha T RDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, 342005, India.
Vidhi JainDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, 342005, India.
Deepak KumarDepartment of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005, India.
Taruna YadavDepartment of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, 342005, India.
Mahendra Kumar GargDepartment of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005, India.
All India Institute of Medical Sciences Jodhpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmpyema necessitans is a rare pulmonary condition described as the presence of pus in the pleural cavity with insidious extension into the surrounding soft tissue. The common microbial aetiology of empyema necessitans is tuberculosis. Nocardiosis a cause of empyema necessitans is rarely described in the literature. We herein present a case of an 80-year-old male with empyema necessitans with osteomyelitis of rib caused by Nocardia farcinica. CASE PRESENTATION: An 80-year-old male presented with complaints of soft swelling on the left lower posterior chest wall associated with dry cough and breathlessness on exertion. Computed Tomography (CT) thorax demonstrated empyema necessitans with features of left fifth rib osteomyelitis. Radiological guided aspiration of the chest wall collection revealed Nocardia species and surgical drainage of abscess was performed. Matrix-assisted laser desorption/ionization time-of-flight-mass spectrometry (MALDI-TOF-MS) identified the isolate as Nocardia farcinica. He was treated with three-drug regimen: Trimethoprim-sulfamethoxazole, amikacin and ceftriaxone for 2 weeks. After showing improvement patient was discharged and advised to take oral Trimethoprim-sulfamethoxazole for the next 6 months with periodic follow-up.

conclusionsAs our case demonstrates, the possibility of invasive Nocardiosis should not be overlooked even in immunocompetent patients. Clinicians should aware of this rare entity while treating patients with empyema necessitans.

Indexed as

EmpyemaNocardiaNocardia InfectionsOsteomyelitisAged, 80 and overHumansMaleRibsCase reportEmpyema necessitansImmunocompetentNocardiaOsteomyelitis

Identifiers

PMID34344324
PMCPMC8336093
OpenAlexW3187466316

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.