Evidence map›Paper›PMID 34344200›Full record

ArticleInternational journal of immunopathology and pharmacology

Positron emission tomography and single photon emission computed tomography imaging of tertiary lymphoid structures during the development of lupus nephritis.

Esmaeil S Dorraji, Ana Oteiza, Samuel Kuttner, Montserrat Martin-Armas, Premasany Kanapathippillai, Sara Garbarino, Gustav Kalda, Mara Scussolini, Michele Piana, Kristin A Fenton

Open access · goldAbstract read
In one paragraph

Article in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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  5. Deep-learning-derived input function in dynamic [Frontiers in nuclear medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Esmaeil S DorrajiRNA and Molecular Pathology Research Group, Institute of Medical Biology, Faculty of Health Sciences, 8016UiT The Arctic University of Norway, Tromsø, Norway.
Ana OteizaNuclear Medicine and Radiation Biology Research Group, Department of Clinical Medicine, Faculty of Health Science, 8016UiT The Arctic University of Norway, Tromsø, Norway.
Samuel KuttnerNuclear Medicine and Radiation Biology Research Group, Department of Clinical Medicine, Faculty of Health Science, 8016UiT The Arctic University of Norway, Tromsø, Norway.ORCID https://orcid.org/0000-0001-7747-9003
Montserrat Martin-ArmasNuclear Medicine and Radiation Biology Research Group, Department of Clinical Medicine, Faculty of Health Science, 8016UiT The Arctic University of Norway, Tromsø, Norway.
Premasany KanapathippillaiRNA and Molecular Pathology Research Group, Institute of Medical Biology, Faculty of Health Sciences, 8016UiT The Arctic University of Norway, Tromsø, Norway.
Sara GarbarinoCentre for Medical Image Computing, Department of Computer Science, University College London, London, UK.
Gustav KaldaNuclear Medicine and Radiation Biology Research Group, Department of Clinical Medicine, Faculty of Health Science, 8016UiT The Arctic University of Norway, Tromsø, Norway.
Mara ScussoliniDipartimento di Matematica, 9302Universita di Genova, Genova, Italy.
Michele PianaDipartimento di Matematica, 9302Universita di Genova, Genova, Italy.
Kristin A FentonRNA and Molecular Pathology Research Group, Institute of Medical Biology, Faculty of Health Sciences, 8016UiT The Arctic University of Norway, Tromsø, Norway.ORCID https://orcid.org/0000-0002-8356-2628
UiT The Arctic University of Norway · NOUniversity of Genoa · ITUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphoid neogenesis occurs in tissues targeted by chronic inflammatory processes, such as infection and autoimmunity. In systemic lupus erythematosus (SLE), such structures develop within the kidneys of lupus-prone mice ((NZBXNZW)F1) and are observed in kidney biopsies taken from SLE patients with lupus nephritis (LN). The purpose of this prospective longitudinal animal study was to detect early kidney changes and tertiary lymphoid structures (TLS) using in vivo imaging. Positron emission tomography (PET) by tail vein injection of 18-F-fluoro-2-deoxy-D-glucose (

Indexed as

AgingAnimalsFluorodeoxyglucose F18KidneyLongitudinal StudiesLupus NephritisMiceMice, Inbred BALB CPancreasPositron-Emission TomographyProspective StudiesRadiopharmaceuticalsTertiary Lymphoid StructuresTomography, Emission-Computed, Single-PhotonFluorodeoxyglucose F18Radiopharmaceuticals18-F-fluoro-2-deoxy-D-glucose99mTC-Nanocolllupus nephritispositron emission tomographysingle photon emission computed tomographysystemic lupus erythematosustertiary lymphoid structures

Identifiers

PMID34344200
PMCPMC8351034
OpenAlexW3190909633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.