ReviewDevelopmental biology2021
Semper's cells in the insect compound eye: Insights into ocular form and function.
Review in Developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Written in the Stars: Astrocyte Biology From Evolution to Disease.Acta physiologica (Oxford, England) · 2026Review
- Cellular innovations and diversity in the lepidopteran compound eye.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Review
- Gap junction-mediated signaling coordinates Rhodopsin coupling for Drosophila color vision.Biology open · 2026Article
- Generation and maintenance of apical rib-like actin fibers in epithelial support cells of the Drosophila eye.Development (Cambridge, England) · 2026Article
- Retinal calcium waves coordinate uniform tissue patterning of theScience (New York, N.Y.) · 2025Article
- Tension transmission across a supracellular network drives increased tissue rigidity in the Drosophila retina.Cell reports · 2025Article
- Brain anatomy of the Cambrian fossil Jianfengia multisegmentalis informs euarthropod phylogeny.Nature communications · 2025Article
- Knockout of a single Pax6 gene (toy but not ey) leads to compound eye deficiency and small head in honeybees.Communications biology · 2024Article
- Mitf, with Yki and STRIPAK-PP2A, is a key determinant of form and fate in the progenitor epithelium of the Drosophila eye.European journal of cell biology · 2024Article
- A Closer Look at Histamine inInternational journal of molecular sciences · 2024Review
- Osmosis as nature's method for establishing optical alignment.Current biology : CB · 2024Article
- Exploring the molecular makeup of support cells in insect camera eyes.BMC genomics · 2023Article
- Probing the conserved roles of cut in the development and function of optically different insect compound eyes.Frontiers in cell and developmental biology · 2023Article
- EyeVolve, a modular PYTHON based model for simulating developmental eye type diversification.Frontiers in cell and developmental biology · 2022Article
- The Rap1 small GTPase affects cell fate or survival and morphogenetic patterning during Drosophila melanogaster eye development.Differentiation; research in biological diversityArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The arthropod compound eye represents one of two major eye types in the animal kingdom and has served as an essential experimental paradigm for defining fundamental mechanisms underlying sensory organ formation, function, and maintenance. One of the most distinguishing features of the compound eye is the highly regular array of lens facets that define individual eye (ommatidial) units. These lens facets are produced by a deeply conserved quartet of cuticle-secreting cells, called Semper cells (SCs). Also widely known as cone cells, SCs were originally identified for their secretion of the dioptric system, i.e. the corneal lens and underlying crystalline cones. Additionally, SCs are now known to execute a diversity of patterning and glial functions in compound eye development and maintenance. Here, we present an integrated account of our current knowledge of SC multifunctionality in the Drosophila compound eye, highlighting emerging gene regulatory modules that may drive the diverse roles for these cells. Drawing comparisons with other deeply conserved retinal glia in the vertebrate single lens eye, this discussion speaks to glial cell origins and opens new avenues for understanding sensory system support programs.
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