Evidence map›Paper›PMID 34343463›Full record

ArticleOpen biology2021

Osmolarity-regulated swelling initiates egg activation in

Anna H York-Andersen, Benjamin W Wood, Elise L Wilby, Alexander S Berry, Timothy T Weil

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Finishing the egg.Genetics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anna H York-AndersenDepartment of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.
Benjamin W WoodDepartment of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.
Elise L WilbyDepartment of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.
Alexander S BerryDepartment of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.
Timothy T WeilDepartment of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.
University of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Egg activation is a series of highly coordinated processes that prepare the mature oocyte for embryogenesis. Typically associated with fertilization, egg activation results in many downstream outcomes, including the resumption of the meiotic cell cycle, translation of maternal mRNAs and cross-linking of the vitelline membrane. While some aspects of egg activation, such as initiation factors in mammals and environmental cues in sea animals, have been well-documented, the mechanics of egg activation in insects are less well-understood. For many insects, egg activation can be triggered independently of fertilization. In

Indexed as

Embryonic DevelopmentAnimalsCalciumCalcium SignalingDrosophila melanogasterDrosophila ProteinsFemaleFertilizationOocytesOsmolar ConcentrationCalciumDrosophila Proteinscalcium waveDrosophilaegg activationosmolarity

Identifiers

PMID34343463
PMCPMC8331238
OpenAlexW3192683904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.