Evidence map›Paper›PMID 34343294›Full record

SynthesisJournal of pediatric psychology2021

Meta-Analysis of Adherence Promotion Interventions in Pediatric Asthma.

Andrea Fidler, Rachel Sweenie, Adrian Ortega, Christopher C Cushing, Rachelle Ramsey, David Fedele

Abstract readMeta-Analysis
In one paragraph

Synthesis in Journal of pediatric psychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The Impact of Adherence and Health Literacy on Difficult-to-Control Asthma.The journal of allergy and clinical immunology. In practice · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea FidlerDepartment of Clinical & Health Psychology, University of Florida.ORCID 0000-0003-2687-020X
Rachel SweenieDepartment of Clinical & Health Psychology, University of Florida.
Adrian OrtegaClinical Child Psychology Program and Schiefelbusch Institute for Life Span Studies, University of Kansas.
Christopher C CushingClinical Child Psychology Program and Schiefelbusch Institute for Life Span Studies, University of Kansas.
Rachelle RamseyDivision of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center.
David FedeleDepartment of Clinical & Health Psychology, University of Florida.ORCID 0000-0003-0896-910X

Funding

Using technology-assisted stepped-care interventions to improve adherence in adolescents with asthmaK23HL139992 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI RAMSEY, RACHELLE R. · 2019 to 2023
$868k
NHLBI NIH HHS K23 HL139992
6 · The paper itself

Abstract

backgroundYouth with asthma commonly have suboptimal adherence to inhaled corticosteroids (ICS). It is critical to systematically evaluate the effectiveness of ICS adherence promotion interventions and discern which techniques are most effective.

objectiveThis study aims to (1) quantify the extent to which interventions improve ICS adherence in pediatric asthma, (2) explore differences in effect size estimates based on intervention and study characteristics, and (3) characterize the risk of bias across interventions.

methodsWe conducted literature searches across five databases. Included studies quantitatively measured ICS adherence as an intervention outcome among youth (<18 years old) diagnosed with asthma and were published after 1997. We analyzed aggregate effect sizes and moderator variables using random-effects models and characterized risk of bias using the Cochrane Collaboration tool.

resultsThirty-three unique studies met inclusion criteria. At post-intervention, the aggregate effect size for pediatric ICS adherence promotion interventions was small but significant (n = 33, g = 0.39, 95% confidence interval [CI] = 0.24-0.54); however, the aggregate effect size at follow-up was not statistically significant (n = 6, g = 0.38, 95% CI = -0.08 to 0.83). Method of adherence measurement and intervention format were significant moderators. Most interventions had a high risk of performance bias and an unclear risk of bias in one or more domains.

conclusionsICS adherence promotion interventions are effective among youth with asthma. Additional longitudinal research is needed to quantify a more precise measure of intervention effectiveness over time, and moderators of intervention effectiveness should be reassessed as the literature base expands.

Indexed as

Anti-Asthmatic AgentsAsthmaAdministration, InhalationAdolescentAdrenal Cortex HormonesChildHumansMedication AdherenceAdrenal Cortex HormonesAnti-Asthmatic Agentsadherenceadolescentasthmachildmeta-analysisself-management

Identifiers

PMID34343294
PMCPMC8521221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.