Evidence map›Paper›PMID 34343216›Full record

ArticlePloS one2021

Cancer burden in Nepal, 1990-2017: An analysis of the Global Burden of Disease study.

Gambhir Shrestha, Rahul Kumar Thakur, Rajshree Singh, Rashmi Mulmi, Abha Shrestha, Pranil Man Singh Pradhan

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Clinical pharmacist interventions on pain management in cancer patients (PharmaCAP) in low resource settings: a multicenter feasibility-pilot randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  8. Comprehensive assessment of pain characteristics, quality of life, and pain management in cancer patients: a multi-center cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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  17. Current practices, gaps, and opportunities on the role of clinical pharmacists in cancer pain management: Perspectives from Nepal.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Gambhir ShresthaDepartment of Community Medicine, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Maharajgunj, Kathmandu, Nepal.ORCID 0000-0002-9975-9804
Rahul Kumar ThakurDepartment of Internal Medicine, Jacobi Medical Center/ Albert Einstein College of Medicine, Bronx, New York, United States of America.ORCID 0000-0003-1740-5939
Rajshree SinghDepartment of Diagnostic Radiology, Mercy Catholic Medical Center, Darby, Philadelphia, United States of America.ORCID 0000-0003-1054-4485
Rashmi MulmiDepartment of Cancer Prevention, Control and Research, B.P. Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal.
Abha ShresthaDepartment of Community Medicine, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.
Pranil Man Singh PradhanDepartment of Community Medicine, Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, Maharajgunj, Kathmandu, Nepal.
Tribhuvan University Teaching Hospital · NPB.P. Koirala Memorial Cancer Hospital · NPCatholic Medical Center · USJacobi Medical Center · USKathmandu University · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCancer is the second leading cause of death and a major public health problem in the world. This study reports the trend and burden of cancer from 1990 to 2017 along with its risk factors in Nepal.

methodsThis study used the database of the Institute of Health Metrics and Evaluation's Global Burden of Diseases on cancer from Nepal to describe the most recent data available (2017) and trends by age, gender, and year from 1990 to 2017. The data are described as incidence, prevalence, disability-adjusted life years (DALY), and percentage change.

resultsIn 2017, the age-standardized cancer incidence and mortality rates were 101.8/100,000 and 86.6/100,000 respectively in Nepal. Cancer contributed to 10% of total deaths and 5.6% of total DALYs in Nepal. The most common cancers were the breast, lung, cervical, stomach and oral cavity cancers. The number of new cancer cases and deaths in Nepal have increased from 1990 to 2017 by 92% and 95% respectively. On the other hand, age-standardized incidence and mortality rates decreased by 5% and 7% respectively. The leading risk factors of cancer were tobacco use, dietary factors, unsafe sex, air pollution, drug use, and physical inactivity.

conclusionsThis study highlighted the burden of cancer in Nepal, contributing to a significant number of new cancer cases, deaths and DALY. A comprehensive approach including prevention, early diagnosis and treatment, and rehabilitation should be urgently taken to reduce the burden of cancer.

Indexed as

Quality-Adjusted Life YearsAdolescentAdultAgedAged, 80 and overAge FactorsChildChild, PreschoolCross-Sectional StudiesFemaleGlobal Burden of DiseaseHumansIncidenceInfantMaleMiddle Aged

Identifiers

PMID34343216
PMCPMC8330909
OpenAlexW3191217683

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.