Evidence map›Paper›PMID 34342837›Full record

ReviewPituitary2021

Pituitary metastases from neuroendocrine neoplasms: case report and narrative review.

Alberto Ragni, Alice Nervo, Mauro Papotti, Nunzia Prencipe, Francesca Retta, Daniela Rosso, Marta Cacciani, Giuseppe Zamboni, Francesco Zenga, Silvia Uccella and 4 more

Open access · hybridAbstract readCase ReportsReview
In one paragraph

Review in Pituitary, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Pituitary metastasis from lung adenocarcinoma.World journal of clinical cases · 2024
    Article
  7. Article
  8. Aggressive Pituitary Tumors and Pituitary Carcinomas: From Pathology to Treatment.The Journal of clinical endocrinology and metabolism · 2023
    Article
  9. Article
  10. Review
  11. The Role of [Cancers · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Alberto RagniOncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Turin, Italy. alberto.ragni@edu.unito.it.ORCID http://orcid.org/0000-0001-9278-8939
Alice NervoOncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.
Mauro PapottiPathology Division, Department of Oncology, University of Turin, Turin, Italy.
Nunzia PrencipeEndocrinology and Metabolism Unit, Department of Medical Sciences, University of Turin, Turin, Italy.
Francesca RettaOncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.
Daniela RossoOncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.
Marta CaccianiEndocrinology Unit, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Giuseppe ZamboniPathology Division, Ospedale Sacro Cuore Don Calabria, Negrar and University of Verona, Verona, Italy.
Francesco ZengaNeurosurgery Unit, Department of Neurosciences and Mental Health, University of Turin, Turin, Italy.
Silvia UccellaPathology Unit, Department of Medicine and Surgery, University of Insubria, Varese, Italy.
Paola CassoniPathology Division, Department of Medical Sciences, University of Turin, Turin, Italy.
Marco GalloEndocrine and Metabolic Diseases Unit, SS. Antonio E Biagio E Cesare Arrigo Hospital, Alessandria, Italy.
Alessandro PiovesanOncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.
Emanuela ArvatOncological Endocrinology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.
University of Turin · ITAzienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo · ITDepartment of Medical Sciences · BYUniversity of Insubria · ITUniversity of Modena and Reggio Emilia · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePituitary metastases (PM) are uncommon findings and are mainly derived from breast and lung cancers. No extensive review of PM from neuroendocrine neoplasms (NENs) is on record. Here we describe a clinical case of PM from pancreatic NEN and review the clinical features of PM from NENs reported in the literature.

methodsA case of PM from a pancreatic NEN followed at our institution is described. We also reviewed the 43 cases of PM from NENs reported in the literature.

resultsA 59-year old female patient, previously submitted to duodeno-cephalo-pancreasectomy for a well-differentiated pancreatic NEN, with known hepatic metastases, underwent a

conclusionsPM from NENs have clinical features similar to metastases derived from other solid tumours, albeit the involvement of the anterior pituitary seems more frequent; a thorough pituitary hormonal evaluation is mandatory, after focused radiological studies, particularly if a surgical approach is considered. The optimal management of PM remains disputed and seems mainly driven by the aggressiveness of the primary tumour and the presence of symptoms. In well-differentiated NENs, particularly in the case of symptomatic PM, surgical removal may be a reasonable approach.

Indexed as

Multiple Endocrine Neoplasia Type 1Neuroendocrine TumorsPituitary NeoplasmsFemaleHumansMiddle AgedPituitary GlandPositron Emission Tomography Computed TomographyHypophysisHypopituitarismNETNeuroendocrine neoplasmNeuroendocrine tumoursSellar metastases

Identifiers

PMID34342837
PMCPMC8416815
OpenAlexW3190083263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.