Evidence map›Paper›PMID 34342743›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2021

Short-term outcomes and healthcare resource utilization following incisional hernia repair with synthetic mesh in patients with Crohn's disease.

B C Perlmutter, H Alkhatib, A L Lightner, A Fafaj, S J Zolin, C C Petro, D M Krpata, A S Prabhu, S D Holubar, M J Rosen

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Article in Hernia : the journal of hernias and abdominal wall surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

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2citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

B C PerlmutterDepartment of General Surgery, Cleveland Clinic, Cleveland, OH, USA.ORCID http://orcid.org/0000-0002-6546-3909
H AlkhatibDepartment of General Surgery, Cleveland Clinic, Cleveland, OH, USA.
A L LightnerDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, USA.
A FafajDepartment of General Surgery, Cleveland Clinic, Cleveland, OH, USA.
S J ZolinDepartment of General Surgery, Cleveland Clinic, Cleveland, OH, USA.
C C PetroDepartment of General Surgery, Cleveland Clinic, Cleveland, OH, USA.
D M KrpataDepartment of General Surgery, Cleveland Clinic, Cleveland, OH, USA.
A S PrabhuDepartment of General Surgery, Cleveland Clinic, Cleveland, OH, USA.
S D HolubarDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, OH, USA.
M J RosenDepartment of General Surgery, Cleveland Clinic, Cleveland, OH, USA. rosenm@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhile the use of synthetic mesh for incisional hernia repair reduces recurrence rates, little evidence exists regarding the impact of this practice on the disease burden of a Crohn's patient. We aimed to describe the post-operative outcomes and healthcare resource utilization following incisional hernia repair with synthetic mesh in patients with Crohn's disease.

methodsA retrospective review of adult patients with Crohn's disease who underwent elective open incisional hernia repair with extra-peritoneal synthetic mesh from 2014 to 2018 at a single large academic hospital with surgeons specializing in hernia repair was conducted. Primary outcomes included 30-day post-operative complications and long-term rates of fistula formation and hernia recurrence. The secondary outcome compared healthcare resource utilization during a standardized fourteen-month period before and after hernia repair.

resultsAmong the 40 patients included, six (15%) required readmission, 4 (10%) developed a surgical site occurrence, 3 (7.5%) developed a surgical site infection, and one (2.5%) required reoperation within the first 30 days. The overall median follow-up time was 42 months (IQR = 33-56), during which time one (2.5%) patient developed an enterocutaneous fistula and eight (20%) experienced hernia recurrence. Healthcare resource utilization remained unchanged or decreased across every category following repair.

conclusionThe use of extra-peritoneal synthetic mesh during incisional hernia repair in patients with Crohn's disease was not associated with a prohibitively high rate of post-operative complications or an increase in healthcare resource utilization to suggest worsening disease during the first 4 years after repair. Future studies exploring the long-term outcomes of this technique are needed.

Indexed as

Crohn DiseaseHernia, VentralIncisional HerniaAdultDelivery of Health CareHerniorrhaphyHumansRecurrenceRetrospective StudiesSurgical MeshTreatment OutcomeCrohn’s diseaseHealthcare resourcesHernia repairInflammationMeshOutcomes

Identifiers

PMID34342743

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.