Evidence map›Paper›PMID 34342580›Full record

ArticleeLife2021

A quadratic model captures the human V1 response to variations in chromatic direction and contrast.

Michael A Barnett, Geoffrey K Aguirre, David Brainard

Abstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Temporal Sensitivity for Achromatic and Chromatic Flicker across the Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael A BarnettDepartment of Psychology, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0002-8355-4601
Geoffrey K AguirreDepartment of Neurology, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0002-4028-3100
David BrainardDepartment of Psychology, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0001-9827-543X

Funding

Scientific TransparencyP30EY001583 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Qi N Cui · 1985 to 2026
$19.5M
COLOR CONSTANCY--REAL IMAGES AND EARLY VISUAL MECHANISMSR01EY010016 · NEI · UNIVERSITY OF PENNSYLVANIA · PI BRAINARD, DAVID H. · 1998 to 2018
$5.4M
NEI NIH HHS P30 EY001583NEI NIH HHS R01 EY010016
6 · The paper itself

Abstract

An important goal for vision science is to develop quantitative models of the representation of visual signals at post-receptoral sites. To this end, we develop the quadratic color model (QCM) and examine its ability to account for the BOLD fMRI response in human V1 to spatially uniform, temporal chromatic modulations that systematically vary in chromatic direction and contrast. We find that the QCM explains the same, cross-validated variance as a conventional general linear model, with far fewer free parameters. The QCM generalizes to allow prediction of V1 responses to a large range of modulations. We replicate the results for each subject and find good agreement across both replications and subjects. We find that within the LM cone contrast plane, V1 is most sensitive to L-M contrast modulations and least sensitive to L+M contrast modulations. Within V1, we observe little to no change in chromatic sensitivity as a function of eccentricity.

Indexed as

Color PerceptionColor VisionContrast SensitivityModels, NeurologicalAdultBrain MappingFemaleHumansMagnetic Resonance ImagingMalePhotic StimulationReproducibility of ResultsTime FactorsVisual CortexVisual PathwaysYoung Adultcolor visioncontrast response functionfMRIforward modelhumanisoresponse contourneuroscienceV1

Identifiers

PMID34342580
PMCPMC8452309

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.