Evidence map›Paper›PMID 34342574›Full record

ArticleeLife2021

CLAMP and Zelda function together to promote

Jingyue Duan, Leila Rieder, Megan M Colonnetta, Annie Huang, Mary Mckenney, Scott Watters, Girish Deshpande, William Jordan, Nicolas Fawzi, Erica Larschan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
6.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 95 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Breaking anterior-posterior symmetry in the moth flybioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Zelda is dispensable forMolecular biology of the cell · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jingyue Duan *Department of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, United States.ORCID 0000-0001-6416-2250
Leila Rieder *Department of Biology, Emory University, Atlanta, United States.
Megan M ColonnettaDepartment of Molecular Biology, Princeton University, Princeton, United States.ORCID 0000-0001-5685-1670
Annie HuangDepartment of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, United States.
Mary MckenneyDepartment of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, United States.
Scott WattersDepartment of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, United States.
Girish DeshpandeDepartment of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, United States.
William JordanDepartment of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, United States.
Nicolas FawziDepartment of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, United States.
Erica LarschanDepartment of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, United States.ORCID 0000-0003-2484-4921
Brown University · USPrinceton University · USEmory University · US

Funding

Developmental Regulation of Nuclear DomainsR35GM142724 · NIGMS · EMORY UNIVERSITY · PI Leila Elizabeth Rieder · 2021 to 2026
$2.6M
Establishment of Active Chromatin DomainsR35GM126994 · NIGMS · BROWN UNIVERSITY · PI LARSCHAN, ERICA NICOLE · 2018 to 2022
$2.0M
Turning off the molecular switch for pathological self-assembly of FUSR01GM118530 · NIGMS · BROWN UNIVERSITY · PI FAWZI, NICOLAS LUX · 2016 to 2020
$1.6M
Mechanisms of Nuclear Body Formation in the Early EmbryoR00HD092625 · NICHD · EMORY UNIVERSITY · PI RIEDER, LEILA ELIZABETH · 2019 to 2021
$640k
Mechanisms of Nuclear Body Formation in the Early EmbryoK99HD092625 · NICHD · BROWN UNIVERSITY · PI RIEDER, LEILA ELIZABETH · 2018 to 2019
$235k
The role of CLAMP, a novel zinc-finger protein, in Drosophila dosage compensationF32GM109663 · NIGMS · BROWN UNIVERSITY · PI RIEDER, LEILA ELIZABETH · 2014 to 2017
$167k
NICHD NIH HHS K99 HD092625NICHD NIH HHS R00 HD092625NIGMS NIH HHS F32 GM109663NIGMS NIH HHS R01 GM118530NIGMS NIH HHS R35 GM126994NIGMS NIH HHS R35 GM142724
6 · The paper itself

Abstract

During the essential and conserved process of zygotic genome activation (ZGA), chromatin accessibility must increase to promote transcription.

Indexed as

Genome, InsectTranscriptional ActivationAnimalsBase SequenceDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsNuclear ProteinsZygoteCLAMP protein, DrosophilaDNA-Binding ProteinsDrosophila ProteinsNuclear Proteinszld protein, DrosophilaCLAMPD. melanogasterDrosophila embryogeneticsgenomicspioneer TFZeldazygotic genome activation

Identifiers

PMID34342574
PMCPMC8367384
OpenAlexW3190519329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.