Evidence map›Paper›PMID 34342542›Full record

ArticlemSystems2021

Identification of a GrgA-Euo-HrcA Transcriptional Regulatory Network in Chlamydia.

Wurihan Wurihan, Yi Zou, Alec M Weber, Korri Weldon, Yehong Huang, Xiaofeng Bao, Chengsheng Zhu, Xiang Wu, Yaqun Wang, Zhao Lai and 1 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. The T3SS structural and effector genes ofFrontiers in cellular and infection microbiology · 2025
    Article
  8. Article
  9. Analyzing RNA-Seq Data frombioRxiv : the preprint server for biology · 2024
    Article
  10. Expression activation of over 70% ofInfection and immunity · 2024
    Article
  11. Article
  12. Requirement of GrgA forbioRxiv : the preprint server for biology · 2023
    Article
  13. Diversity of σJournal of bacteriology · 2023
    Article
  14. Molecular pathogenesis ofFrontiers in cellular and infection microbiology · 2023
    Review
  15. Better In Vitro Tools for ExploringLife (Basel, Switzerland) · 2022
    Article
  16. Robust Heat Shock Response inFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Wurihan WurihanDepartment of Pharmacology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, USA.
Yi ZouGreehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, USA.
Alec M WeberDepartment of Pharmacology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, USA.
Korri WeldonGreehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, USA.
Yehong HuangDepartment of Pharmacology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, USA.
Xiaofeng BaoDepartment of Pharmacology, School of Pharmacy, Nantong Universitygrid.260483.b, Nantong, China.
Chengsheng ZhuDepartment of Microbiology and Biochemistry, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, New Jersey, USA.
Xiang WuDepartment of Parasitology, Central South University Xiangya Medical School, Changsha, Hunan, China.
Yaqun WangDepartment of Biostatistics, School of Public Health, Rutgers University, New Brunswick, New Jersey, USA.
Zhao LaiGreehey Children's Cancer Research Institute, University of Texas Health San Antonio, San Antonio, Texas, USA.
Huizhou FanDepartment of Pharmacology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, USA.
Rutgers, The State University of New Jersey · USThe University of Texas Health Science Center at San Antonio · USCentral South University · CNNantong University · CN

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
High Throughput DNA Sequencer: Illumina HiSeq 3000 SequencerS10OD021805 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAI, ZHAO · 2016 to 2016
$600k
GrgA:a Multifunctional Transcription Factor that Control Chlamydial Gene ExpressionR21AI140167 · NIAID · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI FAN, HUIZHOU · 2019 to 2020
$435k
Exploration of SF3 as a Chemical Probe for Chlamydial BiologyR21AI154305 · NIAID · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI FAN, HUIZHOU · 2020 to 2021
$431k
GrgA: Key Regulator of Chlamydial Physiology and potential Antichlamydial TargetR21AI122034 · NIAID · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI FAN, HUIZHOU · 2016 to 2017
$414k
China Scholarship CouncilHHS | NIH | National Cancer Institute (NCI) CA054174HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI122034HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI140167HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) AI154305HHS | NIH | NIH Office of the Director (OD) OD021805NCI NIH HHS P30 CA054174New Jersey Health Foundation (NJHF) PC 98-20NIAID NIH HHS R21 AI122034NIAID NIH HHS R21 AI140167NIAID NIH HHS R21 AI154305NIH HHS S10 OD021805
6 · The paper itself

Abstract

Chlamydia trachomatis is an obligate intracellular bacterium whose unique developmental cycle consists of an infectious elementary body and a replicative reticulate body. Progression of this developmental cycle requires temporal control of the transcriptome. In addition to the three chlamydial sigma factors (σ

Indexed as

ChlamydiaCT504CTL0766EuoGrgAHrcAtranscriptional regulatory networktranscription factors

Identifiers

PMID34342542
PMCPMC8409740
OpenAlexW3188657758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.