Evidence map›Paper›PMID 34342529›Full record

ArticlemSystems2021

Time-Resolved Proteome Analysis of

Marlène S Birk, Rina Ahmed-Begrich, Stefan Tran, Alexander K W Elsholz, Christian K Frese, Emmanuelle Charpentier

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Investigation ofFoods (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Infant-Type Bifidobacteria as Biocontrol Agents: SuppressingThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marlène S BirkMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Rina Ahmed-BegrichMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Stefan TranMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Alexander K W ElsholzMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Christian K FreseMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Emmanuelle CharpentierMax Planck Unit for the Science of Pathogens, Berlin, Germany.
Max Planck Unit for the Science of Pathogens · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cellular proteome comprises all proteins expressed at a given time and defines an organism's phenotype under specific growth conditions. The proteome is shaped and remodeled by both protein synthesis and protein degradation. Here, we developed a new method which combines metabolic and chemical isobaric peptide labeling to simultaneously determine the time-resolved protein decay and

Indexed as

AAA+adaptationClpChost-pathogen interactionsinfectionListeria monocytogenesmass spectrometryproteolysisproteomicspulsed SILACtandem-mass-tag

Identifiers

PMID34342529
PMCPMC8407217
OpenAlexW3190146547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.