SynthesisDeutsches Arzteblatt international2021
Osteoporotic Fractures of the Thoracic and Lumbar Vertebrae: Diagnosis and Conservative Treatment.
Synthesis in Deutsches Arzteblatt international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- The efficacy and safety of Gukang Capsule for primary osteoporosis: a systematic review and meta-analysis of randomized clinical trial.Frontiers in pharmacology · 2024Pooled it
- Treatment and outcome of osteoporotic OF3 vertebral fractures: results from the prospective multicenter EOFTT study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Fibrinogen-to-albumin ratio links systemic inflammation to osteoporotic fractures and shows discriminative performance together with PLR, NLR, and MLR.Journal of medical biochemistry · 2026Article
- Multivariate Risk Factor Analysis and Clinical Prediction Model Construction of Intercostal Neuralgia Following Single-Segment Osteoporotic Thoracic Vertebral Compression Fractures.International journal of general medicine · 2026Article
- [Postoperative imaging following spinal surgery for traumatic injuries].Radiologie (Heidelberg, Germany) · 2025Article
- Deep Learning Radiomics Model Based on Computed Tomography Image for Predicting the Classification of Osteoporotic Vertebral Fractures: Algorithm Development and Validation.JMIR medical informatics · 2025Article
- Posterior dynamic stabilization in addition to kyphoplasty for surgical management of unstable osteoporotic vertebral compression fractures.Journal of orthopaedic surgery and research · 2025Article
- The influence of sintering of osteoporotic vertebral fractures on the sagittal lumbar profile and degenerative changes.Journal of orthopaedic surgery and research · 2025Article
- Cost-Effectiveness of Artificial Intelligence-Based Opportunistic Compression Fracture Screening of Existing Radiographs.Journal of the American College of Radiology : JACR · 2024Article
- [Conservative fracture treatment in old people].Zeitschrift fur Gerontologie und Geriatrie · 2024Article
- Integrating radiomics with clinical data for enhanced prediction of vertebral fracture risk.Frontiers in bioengineering and biotechnology · 2024Article
- [Osteoporotic vertebral body fractures].Orthopadie (Heidelberg, Germany) · 2023Review
- Automated Rib Fracture Detection on Chest X-Ray Using Contrastive Learning.Journal of digital imaging · 2023Article
- Georg Schmorl prize of the German spine society (DWG) 2022: current treatment for inpatients with osteoporotic thoracolumbar fractures-results of the EOFTT study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Increased incidence of vertebral fractures in German adults from 2009 to 2019 and the analysis of secondary diagnoses, treatment, costs, and in-hospital mortality.Scientific reports · 2023Article
- Clinical Evaluation of the Osteoporotic Fracture Treatment Score (OF-Score): Results of the Evaluation of the Osteoporotic Fracture Classification, Treatment Score and Therapy Recommendations (EOFTT) Study.Global spine journal · 2023Article
- Treatment and Outcome of Osteoporotic Thoracolumbar Vertebral Body Fractures With Deformation of Both Endplates With or Without Posterior Wall Involvement (OF 4): Short-Term Results from the Prospective EOFTT Multicenter Study.Global spine journal · 2023Article
- Spinal Orthoses in the Treatment of Osteoporotic Thoracolumbar Vertebral Fractures in the Elderly: A Systematic Review With Quantitative Quality Assessment.Global spine journal · 2023Article
- Efficacy of cement-augmented pedicle screw fixation for osteoporotic mid-thoracic vertebral fractures.Surgical neurology international · 2023Article
- OF spine classification of osteoporotic thoracolumbar vertebral body fractures by MRI and conventional radiographs only leads to high inter-observer agreement rates-an additional CT adds limited information for the of classification and the OF score.BMC musculoskeletal disorders · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of osteoporotic vertebral body fractures in Europe is 18-26%. Although most of these injuries can be treated conservatively, the underlying concepts have not been defined clearly or uniformly. In this article, we present the current state of the evidence on the diagnosis and conservative treatment of osteoporotic fractures of the thoracic and lumbar vertebrae.
methodsA systematic review of the literature up to May 2020 was carried out in the PubMed and Web of Science Core Collection databases. 549 articles were identified, of which 36 were suitable for inclusion in the review. Articles were sought in the areas of diagnosis, provision of physical aids, pharmacotherapy, physiotherapy, and treatments from the realm of alternative medicine.
resultsThe primary diagnostic technique was conventional x-ray in two planes (with the patient standing, if possible), which had 51.3% sensitivity and 75% specificity. If a fracture was suspected, magnetic resonance imaging (MRI) of the entire spine and regional computed tomography (CT) were carried out. The overall state of the evidence on treatment is poor; the best available evidence is for exercise therapy and physiotherapy, which are supported by three level I and four level II studies. Improvements were seen mainly in mobility and a reduced fear of falling. The use of an active orthosis can be useful as well. No evidence was found on the use of drugs or alternative medicine exclusively in the conservative treatment of osteoporotic vertebral body fractures.
conclusionIt is reasonable to evaluate instability with imaging repeatedly, at regular intervals, over a period of six months. There is still a lack of reliable data on the optimal intensity and duration of physiotherapy, and on the use of orthoses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.