Evidence map›Paper›PMID 34342156›Full record

ArticleInternational wound journal2022

Cost-effectiveness analysis of superabsorbent wound dressings in patients with moderate-to-highly exuding leg ulcers in Germany.

Vladica M Veličković, Mate Szilcz, Zoran Milošević, Thomas Godfrey, Uwe Siebert

Abstract read
In one paragraph

Article in International wound journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vladica M VeličkovićHealth Economics and Outcome Research (HEOR) Department, HARTMANN GROUP, Heidenheim, Germany.ORCID https://orcid.org/0000-0001-7146-1267
Mate SzilczMedical Epidemiology and Biostatistics Department, Karolinska Institute, Stockholm, Stockholm County, Sweden.
Zoran MiloševićFaculty of Medicine, Biostatistics Department, University of Niš, Niš, Serbia.
Thomas GodfreyHealth Economics and Outcome Research (HEOR) Department, HARTMANN GROUP, Heidenheim, Germany.
Uwe SiebertInstitute of Public Health, Medical Decision Making and Health Technology Assessment, UMIT, Hall, Tirol, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aims to estimate the cost-effectiveness of superabsorbent wound dressings compared to the standard-of-care (SoC) dressings mix for treatment of patients with moderate-to-highly exuding leg ulcers in the German healthcare settings. A model-based cost-effectiveness analysis was conducted from the German statutory health insurance perspective, following German specific and international recommendations of good research practice. An individual-level (microsimulation) state-transition model has been used with a cycle length of 1 week and time horizon of 6 months. Several comprehensive systematic reviews were conducted to inform all model inputs, including clinical parameters, efficacy, quality of life, resources utilisation, and cost inputs. In addition, primary data from two clinical trials were used. Based on this cost-effectiveness analysis, using superabsorbent wound dressings instead of the SoC dressings of patients with moderate-to-highly exuding leg ulcers in Germany can lead to an improved healing rate of 2.57% (benefit ratio 1.08), improved health-related quality of life of 0.152 quality-adjusted life weeks, and total direct cost savings of €771 per patient in 6 months. Robustness of results was confirmed in sensitivity and scenario analyses.

Indexed as

Leg UlcerQuality of LifeBandagesCost-Benefit AnalysisHumansWound Healingcost-effectivenessGermanyleg ulcerssuperabsorbent wound dressingswound dressings

Identifiers

PMID34342156
PMCPMC8762557

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.