Evidence map›Paper›PMID 34341958›Full record

ArticlePharmaceutical research2021

Revising Pharmacokinetics of Oral Drug Absorption: II Bioavailability-Bioequivalence Considerations.

Pavlos Chryssafidis, Athanasios A Tsekouras, Panos Macheras

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Pharmaceutical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. AutoPK: Leveraging LLMs and a Hybrid Similarity Metric for Advanced Retrieval of Pharmacokinetic Data from Complex Tables and Documents.International Conference on Tools with Artificial Intelligence : [proceedings]. International Conference on Tools for Artificial Intelligence · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Pavlos ChryssafidisPharmaInformatics Unit, Research Center ATHENA, Athens, Greece.
Athanasios A TsekourasPharmaInformatics Unit, Research Center ATHENA, Athens, Greece.
Panos MacherasPharmaInformatics Unit, Research Center ATHENA, Athens, Greece. macheras@pharm.uoa.gr.ORCID http://orcid.org/0000-0002-1163-5787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore the application of the parameters of the physiologically based finite time pharmacokinetic (PBFTPK) models subdivided in first-order (PBFTPK)

methodsSimulated concentration time data were generated from the Bateman equation and compared with data generated from the (PBFTPK)

resultsThe simulated data of the (PBFTPK)

conclusionThe (PBFTPK)

Indexed as

Biological AvailabilityTherapeutic EquivalencyAdministration, OralArea Under CurveHumansIntestinal AbsorptionModels, BiologicalPharmacokineticsBioavailabilitybioequivalencefinite time of absorptionphysiologically based finite time pharmacokinetic modelsphysiologically based pharmacokinetic models

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.